【Abstract】Objective To investigate the operative methods and the factors affecting the prognosis of congenital intestinal atresia. Methods The clinic data of 40 cases of congenital intestinal atresia was reviewed, including duodenal atresia (6)， jejunal atresia (12)， ileum atresia (20) and colonic atresia (2). The types of atrasia were septal type (10)，blindend type (26), and multisegmental type (4). All had been diagnosed before operation, 4 patients refused the treatment and 26 cases accepted the operation. Results Twenty-six cases of the 36 which accepted operation were cured and survived，the rate of postoperative survival were 72%，postoperative follow-up of 20 patients for 1-21 years had well-pleasing curative effect.Ten cases died postoperatively. Conclusion Operation is the only treatment of this disease，the mode of operation should be selected depending on the site and the type of atresia. The curative effect and the prognosis of this disease are affected by multiple factors.