目的:了解汶川大地震自然灾难对幸存者心理健康状况的影响。方法:在地震发生后1月内采用SCL-90对地震灾区幸存者进行心理健康状况评估。结果:SCL-90各因子分中,躯体化、抑郁、焦虑及敌对因子灾区幸存者均高于常模,其余各因子灾区幸存者均低于常模;男性、女性之间和不同文化程度之间比较, SCL-90总均分及各因子分差异均无统计学意义(P均gt;0.05);不同居住地之间比较,躯体化、恐怖和偏执因子差异有统计学意义。 其中,躯体化症状中,居住农村者均分最高(2.06±1.23),其次为山区幸存者(1.75±0.47),城市幸存者最轻(1.63±0.51)(P= 0.042),而在恐怖、偏执因子分中,居住山区者最高(1.36±0.68;1.59±0.79),其次为农村(1.15±0.39;1.34±0.45),城市最低(1.07±0.30;1.25±0.35)(P均= 0.015)。结论:特大地震自然灾难给幸存者造成的心理创伤很普遍,需要对幸存者进行及时的心理危机干预,政府卫生部门在制定救援政策时有必要纳入心理危机干预计划。
【Abstract】ObjectiveTo detect the expression of human papilloma virus(HPV) 16 E7 was detected in colorectal adenocarcinoma tissue and normal mucosa. MethodsEighty-two patients with primary colorectal adenocarcinoma were selected in this study. The samples were taken from the tumor and the adjacent normal mucosa (10 cm away from the tumor) in each patient. Polymerase chain reaction (PCR) and immunohistochemistry were used to detect HPV16 E7 DNA and protein respectively. ResultsHPV16 E7 DNA expression was significantly higher in colorectal carcinoma (51.22%,42/82) than that in adjacent normal mucosa (4.88%,4/82), P＜0.01. A correlation was found between HPV16 E7 DNA expression and tumor location (P＜0.05)，18.18% in the ascending colon carcinoma and 64.10% in the rectal carcinoma. HPV16 E7 DNA expression was also associated with Dukes stage（P＜0.01）, but was not correlated with cancer differentiation. HPV16 E7 protein expression was mainly dectected in the nuclei of tumor cells with immunohistochemistry. There was a correlation between the expression of HPV16 E7 protein and HPV16 E7 gene. PCR had a higher sensitivity than immunohistochemistry. ConclusionHPV16 infection rate is much higher in the colorectal carcinoma than that in the adjacent normal mucosa, which indicates that HPV16 infection exists in some colorectal carcinomas. The high infection rate of HPV16 E7 is associated with advanced Dukes stage and proximity to anus.
Objective To discuss the mode of triage patient in Emergency Department of West China Hospital of Sichuan University after the Wenchuan earthquake and the major experience during the process. Method The patients’ severity level of injury and waiting time for medical care in Emergency Department were analyzed after earthquake in 2 weeks. Result 375 patients were triaged into the severity level and get the treatment followed the triage systems gave the highest rate of survival and lowest rate of over triage and under triage. Conclusion In the calamity of Wenchuan earthquake with large number of casualties, Emergency Department automatically shifted into disaster mode and triage victims by the irregular triage systems. In this situation, medical staff do not just triage the patients to the Emergency Department or to see a doctor, but triage the victims to the medical care immediately and efficiently. By the new triage system, the West China Hospital saves more lives in less time.
ObjectivesTo investigate the ability of emergency medical rescue personnel in Sichuan province to collect information and contact resources at rescue sites, and to provide evidence for emergency training and drills. MethodsThe rescue site of a batch of critically ill patients in public emergency was simulated. The cross-sectional survey was made on rescue personnel at the city (prefecture) and county level of Sichuan province. The rating scale of on-site information contact ability was used to evaluate their performance. Because the score distribution does not conform to the normal distribution, the space between the median and interquartile was used to describe the score, and multiple measurement data was compared by the rank sum test. ResultsA total of 287 rescue drill personnel were included. The overall score M (P25, P75) of information contact ability was 19.57 (13.04, 28.26). The scores of each dimension were as follows: the safety zone was set as 0 (0, 10), the on-site hazard identification was 0 (0, 16.67), external contact and coordination was 50 (0, 50), internal coordination and command was 50 (16.67, 50), the on-site disaster statistics was 40 (10, 70), the on-site resource status was 0 (0, 0), and the on-site reinforcement demand was 0 (0, 0). Hierarchy by occupation: 19.57 (12.50, 28.26) for clinicians, 19.57 (14.13, 34.78) for nurses, 25 (14.67, 32.61) for medical skills, 21.74 (14.13, 30.44) for public health doctors, and 17.39 (9.78, 21.74) for health management. Hierarchy by titles: 21.74 (13.04, 28.26) for intermediate level, and 17.39 (10.33, 23.91) for advanced level. Scores of different dimensions, occupations and titles were compared respectively, and the differences were statistically significant (P<0.05). ConclusionsThe results of this survey show that the emergency medical rescue personnel at the city (prefecture) and county level of Sichuan province have insufficient overall ability to contact information on site, so those with insufficient ability need to be trained. The training focuses on the on-site resource status, on-site reinforcement demands, safety zone setting and the ability to identify on-site hazards.