目的:观察A型肉毒毒素(BTXA)对面肌痉挛(HFS)患者痉挛程度的改善和生存质量的影响。方法: 对68例HFS患者进行局部注射BTXA,治疗前及治疗后1个月分别对患者的痉挛程度进行判定和使用世界卫生组织生存质量评定量表简表(WHOQOL-BREF)评价生存质量。 结果: 97.04%的HFS患者在BXTA治疗后1个月痉挛明显改善缓解,而且患者在WHOQOL-BREF的生理领域、心理领域、社会关系领域、总的健康状况和总的生存质量的评分均明显高于治疗前,差异有统计学意义(Plt;0.01)。 结论: 局部注射BTXA可迅速缓解或消除HFS患者肌肉痉挛,提高患者的生存质量。
Objective We aimed to evaluate the current status of the construction and practice of the stroke center in West China Hospital of Sichuan University and develope a future strategy to promote the standardized developement of inpatients care and evidence practice. Methods The current status of the Stroke Center in West China Hospital of Sichuan University was assessed. The procedure of diagnosis and treatment was inspected in detail, including triage, thrombolytic therapy, antithrombotic medication and anticoagulant, primary and secondary prevention, filter of risk factors, rehabilitation and education for patients. After that, new plans were made on the basis of the assessment and experiences acquired from practices in the Stroke Center in West China Hospital. Results The primary Stroke Center had been constructed in West China Hospital. The practice in West China Hospital showed that the Stroke Center significantly reduced the mortality and shortened the length of hospital stay of the patients with stroke. Conclusion It is proved that construction and implementation of the Stroke Center in West China Hospital are feasible.