Objective To summarize and further investigate the initial experience of organ procurement process for organ donation after cardiac death (DCD). Methods The clinical data,the selected standard,and the organ procurement process of 28 cases of DCD from July 2009 to January 2012 in the liver transplantation center of Guangzhou General Hospital were reviewed and analyzed. Results Twenty-eight cases of DCD all had donated organs successfully. Among these cases,there were 3 cases (10.7%) of the Maastricht Ⅲ, and one case (3.6%) of the Maastricht Ⅳ,and 24 cases (85.7%) of the organ donation after brain death plus cardiac death (DBCD).Three cases of the Maastricht Ⅲ were practiced the organ procurement process of DCD.One case of the Maastricht Ⅳ was practiced the organ procurement process of DBCD without the extracorporeal membrane oxygenation (ECMO).Twenty-four cases of DBCD were practiced the organ procurement process of DBCD with the ECMO.The donator warm ischemic time was zero min in DBCD,18 min in Maastricht Ⅳ,and mean 25 min (22-28 min) in MaastrichtⅢ.All the donated organs included 28 livers,40 kidneys,and 2 hearts.And all these organs had been practiced the liver transplantation,the kidney transplantation,and the heart transplantation. Conclusions The organ procurement process for organ DCD includes the DCD process and the DBCD process in China,and the later includes the organ procurement process with the ECMO and without the ECMO.The ECMO could well control the warm ischemia for protecting the donors just without ethics dispute. So,the using of the ECMO for the organ DCD of citizen in China has a very important contribution.