摘要:目的:探讨纳络酮对急性酒精中毒的临床疗效及经验。方法: 将58例酒精中毒患者随机分为2组:常规治疗组29例,给予利尿剂、胃肠黏膜保护剂及静脉补液对症治疗;纳络酮治疗组29例,除了应用常规治疗方法外,加用纳络酮。结果:纳络酮治疗组患者症状改善,清醒时间明显提前于对照组(Plt;0.01)。结论: 纳络酮治疗急性酒精中毒疗效肯定、使用简单安全,值得临床推广使用。Abstract: Objective: To evaluate the clinical effect of naoxone on acute alcoholism. Methods: Fiftyeight cases of acute alcoholism were randomly divided into two groups: remedial group (29 cases) and the comparison group (29 cases). Both groups were given diuretic, protection of mucous membrane of stomach and fluid infusion. The remedial group was treated with naloxone. Results: Symptoms of the remedial group were obviously improved. Consciousness was regained much earlier than that of the comparison group (Plt;0.01). Conclusion: Naloxone can be used effectively and safely in treating acute alcoholism.