Objective To analyze the major complications and predictive factors of amputees during postoperative hospitalization, and provide a reference for amputees nursing and early rehabilitation. Methods Using the bibliometric method, we searched Embase, Ovid, Medline, PubMed, CINAHL, China National Knowledge Infrastructure, Wanfang and CQVIP databases for the data of postoperative hospitalization of amputees published from January 1st, 2008 to April 5th, 2022. Statistical description and analysis of article types, sample size, reasons for amputation, amputation sites, complications, influencing factors, predictive factors, and treatment recommendations were performed.Results Finally, 19 articles were included, including 16 in English and 3 in Chinese, all of which were quantitative studies. The literature quality scores were greater than or equal to 7 points, which were all good or excellent. The type of articles were mainly retrospective research (n=15), and the research contents were mainly lower limb amputation. The main reasons for amputation were peripheral vascular disease and diabetes mellitus (n=11). Wound infection, anemia, phantom limb pain, and psychological problems were common complications after amputation. Predictors of complications, secondary operations, and death included age, gender, smoking, drinking, obesity, preoperative comorbidities, level of amputation, anesthesia methods and other factors. Conclusions The focus of acute care after amputation should be wound healing, pain control, proximal physical movement and emotional support, especially for amputees who have prominent postoperative psychological problems. These patients need early psychological disease screening and mental support. After amputation, multi-disciplinary and multi-team coordinated care are needed to achieve both physical and psychological healing of the patient and promote early recovery.
Objective To conduct a bibliometric analysis of research hotspots and development trends in the application of peripheral magnetic stimulation (PMS), systematically review the research evolution, and provide references for future studies. Methods We retrieved PMS-related literature from the Science Citation Index Expanded database in Web of Science Core Collection (January 1, 1989 - March 5, 2025). Using VOSviewer (v1.6.20) and CiteSpace (v6.1.R6), we performed annual publication volume analysis, country/institution/author collaboration network analysis, reference co-citation analysis, and keyword co-occurrence/clustering/burst analysis, with corresponding knowledge mapping visualizations. Results A total of 124 publications were included. Both publication counts and citation frequencies remained low in early years but showed steady annual growth after 2011. The publications originated from 21 countries/regions, with Germany being the most productive nation, Technical University of Munich the leading institution, and Schneider C (from the Research Center of Neuroscience and Rehabilitation Sciences, Laval University, Canada) the most prolific author. Keyword analysis revealed three major research clusters: neuromodulation technologies, physiological mechanisms, and clinical rehabilitation applications. Future research priorities included expanded clinical applications integrating neuroelectrophysiological indicators with rehabilitation assessments, and interdisciplinary optimization of stimulation parameters through engineering approaches. Conclusions PMS has gained widespread clinical application with growing scientific interest. Future studies should focus on current hotspots to advance precision and intelligent development of this technology.
Rapid development is undergoing in the field of rehabilitation robots, and more countries (regions) are participating in international cooperation and becoming academic contributors. Here in this study, the bibliometric method is used to determine the dynamics and developments of international cooperation in China. The publication data are indexed in Web of Science with search term of rehabilitation robot from 2000 to 2019. Compared with other countries (regions), publication with international co-authors and institutes participating in international cooperation are studied by assessment of indicators such as the cooperation degree, cooperation frequency, and the frequency of citations. The results show that in the past two decades, international scientific cooperation has shown a positive tendency in China, and participating in international collaboration could improve China’s impact on the global rehabilitation robot. The United States, England and Japan are the top three countries in number of cooperation with China. Our findings provide valuable information for researchers to better understand China’s international scientific collaboration in rehabilitation robot.
Objective To explore the research trends of traditional Chinese exercise in the rehabilitation of chronic obstructive pulmonary disease (COPD). Methods The Web of Science core collection database was searched to collect literature on traditional Chinese exercise for COPD rehabilitation published from 2004 to 2023. VOSviewer was used for bibliometric analysis of publication year, author, publication institution and country, citation and co-citation information. Results A total of 125 publications were included. No relevant publication was published from 2004 to 2008. Since 2009, the overall number of publications had shown a fluctuating upward trend, with no publications in 2012. From 2019 to 2023, the number of publications on related topics remained at a high level. Reached maximum publication volume in 2020. The annual citation frequency also showed a fluctuating increase, reaching its peak in 2022. Based on comprehensive analysis, Peter M. Wayne and Wu Weibing were the authors with high productivity, high citation, and frequent collaborations. The country with the highest number of publications was China, and the highest institution was Shanghai University of Sport. Initially, the keywords focused on rehabilitation, exercise testing, aerobic exercise, resistance exercise, and respiratory muscle strength. As the times progressed, the focus shifted to lung function, exercise tolerance, and mental health. The current trends included self-management and telemedicine. Conclusions Traditional Chinese exercises have been widely applied in the clinical practice of COPD rehabilitation, showing an upward trend. Facilitating patient self-management and establishing the role and significance of traditional Chinese exercises in remote healthcare for COPD patients may be the focus of future research.
ObjectiveTo explore the present state of research, emerging trends, and key topics in the field of liquid biopsy for lung cancer, offering insights for the holistic management of the disease. MethodsData was sourced from the Web of Science Core Collection database, focusing on literature related to liquid biopsy in lung cancer published between 2012 and 2025. Tools such as CiteSpace and Biblioshiny were employed to perform a detailed visual analysis of various aspects, including publication outputs, contributing countries and institutions, international collaborations, leading authors, prominent journals, academic disciplines, keyword distributions, and cited references. ResultsA total of 1 128 articles were analyzed. Findings indicated that research in the area of liquid biopsy for lung cancer experienced rapid growth since 2014, peaking in 2022. The majority of research efforts were centered in China and the United States. The French institution Institut National de la Sante et de la Recherche Medicale (INSERM) leaded in publication output. Malapelle U was the most prolific author. The journal Cancers published the highest number of related articles. Keywords analysis highlighted liquid biopsy and lung cancer as central research themes. Key research topics consistently included circulating tumor DNA, circulating tumor cells, extracellular vesicles, epidermal growth factor receptor mutations, and DNA methylation in the context of liquid biopsy. Meanwhile, immunotherapy and minimal residual disease emerged as frontier areas in this domain. ConclusionThe bibliometric results demonstrate a continuous rise in scholarly output on liquid biopsy in lung cancer. The identified research hotspots and evolving trends offer valuable guidance for future studies, with the ultimate goal of facilitating broader clinical adoption of liquid biopsy technologies and advancing precision medicine in lung cancer treatment.
The present paper is to evaluate the scientific research level and development trends of biomedical engineering in China using metrology analysis on Chinese biomedical engineering scientific literatures. Pubmed is used to search the biomedical engineering publications in recent 5 years which are indexed by Science Citation Index, and the number and cited times of these publications and the impact factor of the journals are analyzed. The results show that comparing with the world, although the number of the publication in China has increased in recent 5 years, there is still much room for improvement. Among Chinese mainland, Hongkong and Taiwan, Chinese mainland maintains the obvious advantage in this subject, but Hongkong has the highest average cited number. Shanghai and Beijing have better research ability than other areas in Chinese mainland.
Objective To provide some theoretical reference and practical guidance for the medical risk management and early warning of private medical institutions, and to improve the service level and social reputation of private medical institutions. Methods China National Knowledge Infrastructure, Wanfang, VIP, and Web of Science database were searched for literature on medical risk management of private medical institutions published from the dates of establishment of databases to July 31, 2023. CiteSpace software was used for analysis. The aspects of literature number, literature source, author-institution cooperation, keyword co-occurrence, keyword clustering and burst were analyzed. Results A total of 2 635 literature were detected. Among them, there were 1446 articles in Chinese and 1189 articles in English. Although domestic research started late, it covered a wide range of disciplines and research fields. The Chinese literature showed a growth trend in the medium term, but the growth trend was slower than that of foreign literature. At the same time, the cooperation network of foreign authors and institutions was closer than that of domestic ones, and the overall development was relatively insufficient. There were differences between domestic and foreign research hotspots in terms of disciplines and research contents. Conclusions It is necessary to strengthen the theoretical and practical research on medical risk management of private medical institutions, and accelerate the construction of risk management and early warning models suitable for the characteristics of private medical institutions in China. In the future, the emerging research fields such as moral hazard, emergency and internal control need to be deepened and expanded.
ObjectiveTo understand the authors, countries/regions, institutions, journals and hot topics about the application research of indocyanine green (ICG) in hepatobiliary surgery. MethodsThis study conducted a bibliometric analysis of the literatures on the application of ICG in hepatobiliary surgery in the Web of Science Core Collection from 2008 to 2024. CiteSpace software was used to evaluate and visualize collaborative networks and hot topics. ResultsA total of 2 267 literatures were included in this study, with a citation frequency of 50 463 times. The literatures from Japan accounted for the highest proportion, and most of the papers (13.50%) were published by Kokudo N. In China, Tian Jie had published the largest number of papers (33 articles). The research hotspots focused on liver resection, bile duct surgery, liver transplantation, and tumors, with recent hotspots including “liver preservation” and “rejection” frequently appearing. ConclusionThis study aims to present the overall state and trend of the application research of ICG in hepatobiliary surgery through data capture and induction, and providing valuable references for clinicians and researchers.
Objective To review the research hotspots and cutting-edge dynamics in the field of hospital operations management, providing references for relevant research in our country. Methods Using CiteSpace 6.1.R6 software, we conducted a visual analysis of English literature in the field of hospital operations management collected from the Web of Science database Core Collection from the establishment of the database to December 31st 2022. Result A total of 808 articles were included, with the first article in the field of hospital operations management published in 1980 since the establishment of the Web of Science database. Over the 42-year period, annual publications had shown an increasing trend. Research outcomes were concentrated in institutions and researchers from Europe and the United States, but academic collaboration among institutions and authors was not particularly close. The hotspots in related fields mainly focused on aspects of care quality, management, and performance. Conclusions Studies on hospital operations management in China are in the early stage, and the international influence of research outcomes needs to be further strengthened. The research frontier has shifted from healthcare quality and safety to internal financial performance, human resource management, and resource allocation. Research on the application of technological methods in hospital operations management will continue to emerge.
Objective To explore the global research status and trends of continuous renal replacement therapy (CRRT) based on knowledge visualization analysis. Methods Based on the Web of Science Core Collection, studies reporting CRRT research that were published between June 2014 and June 2023 were retrieved and collected after manual review. VOSviewer and CiteSpace softwares were used for bibliometric visualization analysis, including publication trends, geographical distribution characteristics, journal distribution characteristics, author contributions, citations, funding source characteristics, and keyword clustering. Results A total of 2708 papers were analyzed, with an increasing trend in the number of articles and citation frequency from 2015 to 2021. The United States was the most prolific country and France was the most influential country. The University of Pittsburgh in the United States had the highest number of publications among research institutions and showed higher motivation for inter-institutional collaboration. The University of Queensland in the Australia had the highest average citation frequency. Professor Rinaldo Bellomo of Australia was the most productive author and Professor Jeffrey Lipman was the most influential. Jason A. Roberts, Jeffrey Lipman and Claudio Ronco were the three authors who had the highest number of collaborations with other authors. Keyword cluster analysis showed that the prognosis of CRRT for renal disease was the focus of research, with hotspots of research being antibiotics, citrate accumulation, plasma replacement, lactate clearance, acute respiratory distress syndrome, and coronavirus disease 2019. Coupling analysis of the literature showed that exploring the indications for CRRT and optimizing treatment prescription were at the forefront of research. Conclusions The present study of CRRT has generally shown an upward trend in the last decade. The management and efficacy of CRRT remains a hot topic of research. Exploring the indications for CRRT and optimizing treatment prescriptions may be a popular research direction and trend in the future.