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find Keyword "disease burden" 3 results
  • Interpretation of the key points of the 2022 White Paper on the Quality of Life of Chinese Lung Cancer Patients

    Recently, sponsored by the Science Popularization Department of the China Anti Cancer Association, jointly organized by the Rehabilitation Branch of the China Anti Cancer Association and the Mijian Digital Cancer Patient Course Management Platform, and co-organized by the Science Popularization Special Committee of the China Anti Cancer Association, The "2022 White Paper on the Quality of Life of Chinese Lung Cancer Patients" has been officially released (herein after referred to as the "White Paper"), which mainly elaborates on the basic situation of Chinese lung cancer patients and the medical, social, and economic impacts caused by the disease. This article interprets the White Paper in order to help the public understand the real situation of lung cancer patients and provide important empirical evidence and valuable insights for the diagnosis, treatment, and rehabilitation of lung cancer in China.

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  • Trends in Chinese esophageal cancer burden of disease due to high alcohol use and comparative analysis of males and females from 1990 to 2019

    Objective To integrate and analyse the burden of disease of oesophageal cancer due to alcohol consumption and the differences between males and females in China from 1990 to 2019, and to predict the trend of change in the burden of disease from 1990 to 2019, in order to improve its prevention and treatment strategies. Methods Data on the burden of disease of oesophageal cancer due to alcohol consumption in China from 1990 to 2019 were extracted from the Global Burden of Disease (GBD) 2019 database and integrated and analysed, and the corresponding trends were analysed by the Joinpoint regression model using Joinpoint 4.9.1.0 software. The grey prediction model [GM (1, 1)] was used to predict the disease burden status of oesophageal cancer attributable to alcohol consumption in China from 2020 to 2029. Results Oesophageal cancer attributable to tobacco, alcohol consumption, high BMI, and insufficient fruit and vegetable intake accounted for the first, second, third, fourth, and fifth largest number of oesophageal cancer deaths in 2019 in China, respectively. In terms of gender, the number of deaths and the standardised mortality rate of males in 2019 were 18.97 and 20.00 times higher than those of females, respectively; the number of DALYs and the standardised DALYs rate of females in 2019 were 33.08 and 24.78 times higher than those of females, suggesting that the disease burden of oesophageal cancer due to alcohol consumption is higher among females in China. From 1990 to 2019 Chinese oesophageal cancer due to alcohol consumption, the AAPC values for the number of deaths and the number of DALYs were 2.08% and 1.63%, respectively, which showed an increasing trend, and the change trend was statistically significant (P<0.05); the AAPC values for the standardised death rate and the rate of standardised DALYs were -0.92% and -1.23%, respectively, which showed a decreasing trend, and the change trend was statistically significant (P<0.05). The overall burden of disease for all age groups from 1990 to 2019 showed an increasing trend, with both their mortality and DALYs rates increasing with age, and the elderly population aged 55 years or older was the main group of the burden of disease. The grey prediction model showed that the overall standardised mortality rate and standardised DALYs rate declined to 2.94/100 000 and 67.94/100 000, respectively, by 2029, with a greater decline in females than in females. Conclusion Although the burden of disease for alcohol-induced oesophageal cancer in China has decreased over the past 30 years, it is still low compared with the overall burden of disease for oesophageal cancer, and the burden of disease for females is much higher than that for females. Focusing on prevention and treatment for males and the elderly remains a major problem for drinking-induced oesophageal cancer in China.

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  • Aortic aneurysm burden among young adults in China from 1990 to 2019: Data from Global Burden of Disease Database 2019

    ObjectiveTo provide reference for the formulation of public health policies through exploring the disease burden of aortic aneurysm (AA) in Chinese young adults. MethodsWe analyzed sex-specific mortality rates and years of life lost (YLLs) among Chinese young adults with AA in Global Burden of Disease (GBD) database from 1990 to 2019, and compared with global and young adult AA data stratified by sociodemographic index (SDI). Joinpoint was used to analyze the time trend of AA burden among young males and females in China. The attributable risk factors for AA burden in young adults and explore its characteristics were analyzed. ResultsAmong young adults (15-39 years old) in China, the total of AA deaths in 2019 was 657 (95%UI 549-791), an increase of 16.90% compared with 1990. The mortality rate in 2019 was 0.13 per 100 000 (95%UI 0.11-0.16), with an increase of 30.00% compared with 1990. In 2019, a total of 36921 YLLs (95%UI 30 865-44 445) were produced by young adults in China, with an increase of 13.21% compared with 1990. The YLLs rate was 7.42 per 100 000 (95%UI 6.20-8.93), with an increase of 24.92%. The male YLLs rate was 11.49 per 100 000 (95%UI 9.22-14.28), with an increase of 35.18%. The female YLLs rate was 3.11 per 100 000 (95%UI 2.36-3.98), with a decrease of 3.12%. Both the AA mortality rate and YLLs rate in male young adults were higher than those in female young adults, and the growth rate from 1990 to 2019 was significantly higher than that in females. ConclusionThe disease burden of AA among young adults in China increases significantly from 1990 to 2019, mainly among males. The time trend of male and female AA YLLs in Chinese young adults is obviously inconsistent. The AA YLLs of Chinese male young adults are positively correlated with economic development and the progress of medical technology, and are in the process of gradual increase. The AA YLLs of Chinese female young adults are much lower than the average level, which is closely related to the low smoking rate.

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