ObjectiveTo investigate current status and hot issues of pancreatic neuroendocrine neoplasm (pNEN) imaging research.MethodsThe literatures focusing on pNEN and published from 1998 to 2018 were retrieved from the core database of Web of Science. The quantitative analysis of literatures was then conducted by using the CiteSpace software based on the bibliometrics method. The research trend was then summarized systematically and the potential research fronts and focuses were explored.ResultsA total of 190 articles in the field of pNEN imaging research were retrieved, and the top three countries in the literatures were the United States, Germany, and Italy. The clustering of co-citation of pNEN included the endoscopic ultrasound, current diagnosis, prospective evaluation, cystic pancreatic neuroendocrine tumor, hypervascular neuroendocrine tumor, nonfunctioning pancreatic neuroendocrine tumor, intravoxel incoherent motion, and metastastic lesion. The hot of keywords in the field of pNEN included the fine needle aspiration, CT, diagnosis, pancreas, cancer, neuroendocrine tumor, neoplasm, carcinoma, and management. The hot keywords clustering had the neuroendocrine tumor, pancreatic mass size, non-hyperfunctioning neuroendocrine tumor, CT appearance, metastatic lesion, ancillary studies, somatostatin analogues, somatostatinoma, intraoperative ultrasound, and multiple endcorine neoplasia 1.ConclusionAccurate imaging diagnosis of pNEN is still a hot issue in this field.
ObjectiveTo investigate the current status and hotspots in researches of gastrointestinal stromal tumor.MethodsThe literatures related to gastrointestinal stromal tumor and published from 2000 to 2019 were extracted from Web of Science Core Collection. Visualization analysis was conducted by utilizing CiteSpace and VOSviewer software based on bibliometrics methods.ResultsA total of 3 226 articles and reviews were retrieved. The number of publications increased from 2000 to 2019, from the initial 34 publications gradually increased to 241 in 2019, and the maximum number of publications was 265 in 2015. The most productive five countries in terms of publication number were: 907 in the United States, 540 in China, 522 in Japan, 219 in Germany, and 214 in Italy. Co-occurrence networks of keywords were divided into three clusters: targeted therapy, clinical management, and pathogenesis research. Co-citation analysis of literatures contained 9 clusters, and cluster #0 prognosis was the latest cluster, indicating the research frontier and tendency.ConclusionsThe United States and its domestic institutes are the pioneers. Targeted therapy, clinical management, and pathogenesis researches are the main research filed. Prognosis research may be the new research tendency, and clinical and basic researches are still hotspots in medical research.