This study evaluated the cytotoxicity of a new type silicone rubber for maxillofacial prosthesis, which was developed by the present authors. According to the GB/T16886.5-2003, the samples were prepared and tested with cell counting kit-8 (CCK-8) assay, the relative growth rate (RGR) was calculated, and morphology of L929 cells were observed by scanning electron microscope and phase contrast microscope. The results showed that RGR of L929 cells were 91.65% (24 h), 87.03% (48 h), 87.30% (72 h), respectively, and the level of cytotoxicity was grade 1. The L929 cells showed typical fusiform shape and their morphology did not changed significantly after 24 h, 48 h and 72 h. These data indicated that the newly-developed silicone rubber material, as a maxillofacial prosthesis material, should be a safe biomaterial.
ObjectiveTo compare the application of impression made with machine mixed silicone rubber and alginate on fixed partial denture. MethodsThe fixed prosthesis oral cavity repair patients were continuously enrolled who visited the department of Oramaxillofacial Surgery of West China Stomatology Hospital, Sichuan University form June 2010 to January 2011. They were randomly divided into two groups (machine mixed silicone rubber group and alginate group). After conventional row for teeth, both materials were used to make impression. Then, bubble condition and its grade caused by dental impression were evaluated. Statistical analysis has performed using SPSS 15.0. ResultsA total of 50 fixed prosthesis oral cavity repair patients were included, of which, 25 were in the machine mixed silicone rubber group and 25 in the alginate group. Compared with alginate, the impression made with machine mixed silicone rubber was higher of grade (Z=-3.890, P < 0.001), smoother (t=4.196, P < 0.001), higher precision than the alginate group. ConclusionCompared with alginate, the mixed silicone rubber for making oral fixed prosthesis machine impression is higher in precision, clearer in the gum line, which is good for late production of denture.