The image characteristics of spectral-domain optical coherence tomography on retinal tuft_Chinese Journal of Ocular Fundus Diseases

Authors：

 Li Haidong , Chen Lifeng , Wang Jun , Lian Hengli , Zhang Zhewen

Eye Hospital of Wenzhou Medical University at Hangzhou, Hangzhou 310020, China;

Corresponding author：

Li Haidong, Email: dreamagain@163.com

Keywords：

Tomography, optical coherence; Retinal tuft; Imaging feature

DOI：

10.3760/cma.j.cn511434-20210917-00531

Video：

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Objective To describe the spectral-domain optical coherence tomography (SD-OCT) features of retinal tuft. Methods A retrospective clinical study. From May 2019 to April 2020, 22 patients (22 eyes) diagnosed as retinal tuft by clinical fundus examination in Eye Hospital of Wenzhou Medical University at Hangzhou were included in the study. There were 9 eyes in 9 males and 13 eyes in 13 females. All patients underwent ultra-widefield laser scanning fundus photography and SD-OCT examination. SD-OCT was performed with a 55° wide-angle lens to observe the morphology, color, size and location of the lesions. Results Twenty-six retinal tuft lesions were found in 22 eyes, all of which were solitary, gray, thylakoid and protrusion. SD-OCT images showed that all the lesions of retinal tuft showed a local protuberant appearance with moderate and hyperreflectivity, which was higher than the surrounding retina plane. In 22 lesions (84.62%, 22/26), there were one or more irregular hyporeflective cavities between the retinal neuroepithelial layers, and the other 4 lesions (15.38%,4/26) contained no hyporeflective cavities. In addition, 23 cases (88.46%, 23/26) with hyperreflective condensed cortical vitreous attached to the retina at the top of lesions, 8 cases (30.77%, 8/26) with retinal tear, and 6 cases (23.08%, 6/26) with shallow retinal detachment. Conclusions In SD-OCT, the retinal tufts show moderate and strong local protrusion, which are higher than the surrounding retinal plane. In most of the lesions, there are multiple or single irregular weak reflex cavities, and there are hyperreflective condensed cortical vitreous attached to the retina at the top of lesions. Local retinal tears or shallow retinal detachment are present in some lesions.

Citation： Li Haidong, Chen Lifeng, Wang Jun, Lian Hengli, Zhang Zhewen. The image characteristics of spectral-domain optical coherence tomography on retinal tuft. Chinese Journal of Ocular Fundus Diseases, 2022, 38(11): 891-894. doi: 10.3760/cma.j.cn511434-20210917-00531 Copy

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2. Sebag J. Vitreous and vitreoretinal interface[M]//Andrew P. Ryan's Retina. 6th ed. Amsterdam: Elsevier, 2018: 544-581.
3. Byer NE. Cystic retinal tufts and their relationship to retinal detachment[J]. Arch Ophthalmol, 1981, 99(10): 1788-1790. DOI: 10.1001/archopht.1981.03930020662007.
4. Cuenca N, Ortuño-Lizarán I, Sánchez-Sáez X, et al. Interpretation of OCT and OCTA images from a histological approach: clinical and experimental implications[J/OL]. Prog Retin Eye Res, 2020, 77: 100828[2020-01-03].https://pubmed.ncbi.nlm.nih.gov/31911236/. DOI: 10.1016/j.preteyeres.2019.100828.
5. Curcio CA, Zanzottera EC, Ach T, et al. Activated retinal pigment epithelium, an optical coherence tomography biomarker for progression in age-related macular degeneration[J]. Invest Ophthalmol Vis Sci, 2017, 58(6): 211-226. DOI: 10.1167/iovs.17-21872.
6. 李海东, 王君, 徐小琼, 等. 广角频域光相干断层扫描观察囊性视网膜突起二例[J]. 中华眼底病杂志, 2021, 37(4): 313-314. DOI: 10.3760/cma.j.cn511434-20200506-00195.Li HD, Wang J, Xu XQ, et al. Two cases of cystic retinal tuft as observed by widefield spectral-domain optical coherence tomography[J]. Chin J Ocul Fundus Dis, 2021, 37(4): 313-314. DOI: 10.3760/cma.j.cn511434-20200506-00195.
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8. Lai WY, Tseng CL, Wu TT, et al. Correlation between baseline retinal microstructures in spectral-domain optic coherence tomography and need for early intervention in central serous chorioretinopathy[J/OL]. BMJ Open Ophthalmol, 2017, 2(1): e000054[2017-08-16]. https://pubmed.ncbi.nlm.nih.gov/29354717/. DOI: 10.1136/bmjophth-2016-000054.
9. Gregori NZ, Lam BL, Gregori G, et al. Wide-field spectral-domain optical coherence tomography in patients and carriers of X-linked retinoschisis[J]. Ophthalmology, 2013, 120(1): 169-174. DOI: 10.1016/j.ophtha.2012.07.051.
10. Uji A, Yoshimura N. Application of extended field imaging to optical coherence tomography[J]. Ophthalmology, 2015, 122(6): 1272-1274. DOI: 10.1016/j.ophtha.2014.12.035.
11. Choudhry N, Golding J, Manry MW, et al. Ultra-widefield steering-based spectral-domain optical coherence tomography imaging of the retinal periphery[J]. Ophthalmology, 2016, 123(6): 1368-1374. DOI: 10.1016/j.ophtha.2016.01.045.
12. Taney LS, Baumal CR. Optical coherence tomography of a cystic retinal tuft[J]. JAMA Ophthalmol, 2014, 132(10): 1191. DOI: 10.1001/jamaophthalmol.2014.190.
13. 李永平, 李彬. 眼科病理学发展与精准医学[J]. 中华眼科杂志, 2016, 52(10): 724-727. DOI: 10.3760/cma.j.issn.0412-4081.2016.10.002.Li YP, Li B. Development of ophthalmic pathology and precision medicine[J]. Chin J Ophthalmol, 2016, 52(10): 724-727. DOI: 10.3760/cma.j.issn.0412-4081.2016.10.002.

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