• 1. Department of Ophthalmology, Shanghai Eye & ENT Hospital of Fudan University, Shanghai 200031, China; Department of Ophthalmology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, China;
  • 2. ;
Chen Ling, Email: linglingchen98@hotmail.com
Export PDF Favorites Scan Get Citation

Cancer immunotherapy refers to the therapeutic effect of controlling or eliminating tumor cells by interfering with the immune system to restore the anti-tumor immune response. Immune checkpoint inhibitor therapy that blocks programmed death -1/programmed cell death ligand-1/cytotoxic T lymphocyte-associated antigen 4 is one of the most commonly used tumor immunotherapies, with good efficacy and wide application. These drugs cause immune-related ocular complications such as uveitis, autoimmune retinopathy, and scleritis, which represent a new etiology of ocular inflammation. The ophthalmologist's grasp of the clinical characteristics of these diseases is helpful for timely diagnosis. At the same time, the ophthalmologist will work closely with the oncologist to make a comprehensive judgment based on the patient's primary tumor, survival prognosis, severity of adverse reactions related to ocular immunotherapy, and visual prognosis, and develop suitable therapeutic strategie, thereby saving the patients' vision and improving the quality of life.

Citation: Chen Ling, Ma Yixian, Wang Wei, Xu Gezhi. Pay attention to the diagnosis and treatment of fundus complications related to tumor immunotherapy. Chinese Journal of Ocular Fundus Diseases, 2022, 38(5): 341-345. doi: 10.3760/cma.j.cn511434-20220311-00130 Copy

  • Next Article

    Changes of aqueous cytomegalovirus DNA in patients with cytomegalovirus retinitis after allogeneic bone marrow hematopoietic stem cell transplantation