• 1. Department of Ophthalmology, The First Affiliated Hospital of Hunan Normal University, Hunan Provincial People's Hospital, Changsha 410000, China;
  • 2. Department of Ophthalmology, The Second Xiangya Hospital of Central South University, Changsha 410000, China;
  • 3. Changsha Aier Eye Hospital, Changsha 410000, China;
Duan Xuanchu, Email: duanxchu@csu.edu.com
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The lamina cribrosa (LC) is a complicated collagenous meshwork of trabeculae and laminar pores contain capillaries, nerves and neurogliocytes, which provides structural and nutrient support to the retinal ganglion cell axons as they exit the eye. The intraocular pressure causes direct damage or deformation and remodeling of LC, leads to axoplaxmic transport and blood supply disturbance. The preponderance of evidence suggests that LC is the principal site of glaucomatous damage. The development of optic coherence tomography (OCT) technology has improved the imaging quality of deep structures of the optic nerve head and makes it possible to detect LC. The quantitative research indexes of LC structure include LC depth, laminar curvature, laminar thickness, prelaminar tissue, laminar pore, laminar defect and hemodynamics. To improve the understanding of LC structure, explore the characteristics of LC and understand the biomechanical and hemodynamic pathogenesis of glaucoma, which would be contribute to the application of big data research in the diagnosis and treatment of glaucoma.

Citation: Luo Haomin, Zhou Dengming, Duan Xuanchu. Clinical application and new progress of optical coherence tomography in detecting lamina cribrosa structure. Chinese Journal of Ocular Fundus Diseases, 2021, 37(2): 153-157. doi: 10.3760/cma.j.cn511434-20200409-00152 Copy

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