小儿ChiariⅠ型畸形合并脊髓空洞症研究进展_West China Medical Journal

Authors：

 周雯 ¹ , 刘家刚 ² ,  黄思庆 ²

1. ;
2. ;

Corresponding author：

黄思庆, Email: brainspine2010@163.com

Keywords：

小儿Chiari Ⅰ型畸形; 脊髓空洞; 研究进展

DOI：

10.7507/1002-0179.20140421

Video：

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小儿Chiari Ⅰ型畸形合并脊髓空洞症临床少见，患儿临床症状较少、隐袭且与成年人有很大区别，容易发生误诊、误治。随着MRI的广泛应用，该疾病诊断数量日渐增多，但目前关于小儿Chiari Ⅰ型畸形合并脊髓空洞症的研究存在较多争议，临床工作者对其认识和诊治水平尚待提高。根据国内外文献、专著及最新临床试验研究成果，现就小儿Chiari Ⅰ型畸形合并脊髓空洞症研究进展进行综述。

Citation： 周雯, 刘家刚, 黄思庆. 小儿ChiariⅠ型畸形合并脊髓空洞症研究进展. West China Medical Journal, 2014, 29(7): 1376-1379. doi: 10.7507/1002-0179.20140421 Copy

1.	Rocque BG, George TM, Kestle J, et al. Treatment practices for Chiari malformation type Ⅰ with syriongomylia:results of a survey of the American Society of Pediatric Neurosurgeons[J]. J Neurosurg Pediatr, 2011, 8(5):430-437.
2.	Winn HR, Kliot M, Brem H, 等. 尤曼斯神经外科学(第3卷):功能性神经外科、疼痛与小儿神经外科[M]. 5版. 王任直, 译. 北京:人民卫生出版社, 2009:2679-2690.
3.	Tubbs RS, Beckman J, Naftel RP, et al. Institutional experience with 500 cases of surgically treated pediatric Chiari malformation type Ⅰ[J]. J Neurosurg Pediatr, 2011, 7(3):248-256.
4.	Brockmeyer DL. The complex Chiari:issues and management strategies[J]. Neurol Sci, 2011, 32(S3):S345-S347.
5.	Oldfield EH, Muraszko K, Shawker TH, et al. Pathophysiology of syringomyelia associated with Chiari Ⅰ malformation of the cerebellar tonsils[J]. J Neurosurg, 1994, 80(1):3-15.
6.	伊卫宁, 游潮. 脊髓空洞症发病机制研究进展[J]. 中国现代神经疾病杂志, 2009, 2(9):117-119.
7.	王斌, 邱勇, 俞杨, 等. 青少年伴发脊柱侧凸的Chiari畸形的治疗策略[J]. 中华小儿外科杂志, 2004, 25(2):163-167.
8.	Albert GW, Menezes AH, Hansen DR, et al. Chiari malformation Type I in children younger than age 6 years:presentation and surgical outcome[J]. J Neurosurg Pediatr, 2010, 5(6):554-561.
9.	陈春红, 吴沪生, 齐翔, 等. 儿童脊髓空洞症12例临床特征和诊断[J]. 中华儿科杂志, 2001, 33(8):497-498.
10.	焦颖, 李光乾. 小儿脊髓空洞症8例临床分析[J]. 中国实用神经疾病杂志, 2007, 10(1):101-102.
11.	Mottolese C, Szathmari A, Simon E, et al. Treatment of Chiari type Ⅰ malformation in children:the experience of Lyon[J]. Neurol Sci, 2011, 32(11):S325-S330.
12.	Tokunaga M, Minami S, Isobe K, et al. Natural history of scoliosis in children with syringomyelia[J]. J Bone Joint Surg Br, 2001, 83(3):371-376.
13.	郑冬凌, 郝彦峰, 吕茂利, 等. 小儿脊髓空洞症1例[J]. 实用医学杂志, 2007, 23(9):1417.
14.	Durham SR, Fjeld-Olenec K. Comparison of posterior fossa decompression with and without dura plasty for the surgical treatment of Chiari malformation typeⅠin pediatric patients:a metaanalysis[J]. J Neurosurg Pediatr, 2008, 2(7):42-49.
15.	Tao W, Zezhang Z, Jian J, et al. Syrinx resolution after posterior fossa decompression in patients with scoliosis secondary to Chiari malformation type Ⅰ[J]. Eur Spine J, 2012, 21(6):1143-1150.
16.	Kan D, Yong-ning L, Gui-lin L, et al. Neural endoscopic assisted micro-invasive management of Chiari Ⅰ malformation[J]. Chin Med J, 2010, 123(14):1878-1883.
17.	Krieger MD, Falkinstein, Bowen IE, et al. Scoliosis and Chiari malformation Type I in children[J]. J Neurosurg Pediatr, 2011, 7(1):25-29.
18.	Galarza M, Sood S, Ham S. Relevance of surgical strategies for the management of pediatric Chiari type Ⅰ malformation[J]. Childs Nerv Syst, 2007, 23(6):691-696.
19.	Fenoy AJ, Menezes AH, Fenoy KA. Craniocervical junction fusions in patients with hindbrain herniation and syringohydromyelia[J]. J Neurosurg Spine, 2008, 9(7):1-9.
20.	Junpeng M, Chao Y, Haifeng C, et al. Cerebellar tonsillectomy with suboccipital decompression and duraplasty by small incision for Chiari Ⅰ malformation (with syringomyelia):long term follow-up of 76 surgically treated cases[J]. Turk Neurosurg, 2012, 22(3):274-279.
21.	Novegno F, Caldarelli M, Massa A, et al. The natural history of the Chiari TypeⅠ anomaly[J]. J Neurosurg Pediatr, 2008, 2(9):179-187.
22.	Singhal A, Bowen-Robert T, Steinbok P, et al. Natural history of untreated syringomyelia in pediatric Patients[J]. Neurosurg Focus, 2011, 31(6):1-5.
23.	Strahle J, Muraszko KM, Kapurch J, et al. Natural history of Chiari malformation Type Ⅰ following decision for conservative treatment[J]. J Neurosurg Pediatr, 2011, 8(8):214-221.

1. Rocque BG, George TM, Kestle J, et al. Treatment practices for Chiari malformation type Ⅰ with syriongomylia:results of a survey of the American Society of Pediatric Neurosurgeons[J]. J Neurosurg Pediatr, 2011, 8(5):430-437.
2. Winn HR, Kliot M, Brem H, 等. 尤曼斯神经外科学(第3卷):功能性神经外科、疼痛与小儿神经外科[M]. 5版. 王任直, 译. 北京:人民卫生出版社, 2009:2679-2690.
3. Tubbs RS, Beckman J, Naftel RP, et al. Institutional experience with 500 cases of surgically treated pediatric Chiari malformation type Ⅰ[J]. J Neurosurg Pediatr, 2011, 7(3):248-256.
4. Brockmeyer DL. The complex Chiari:issues and management strategies[J]. Neurol Sci, 2011, 32(S3):S345-S347.
5. Oldfield EH, Muraszko K, Shawker TH, et al. Pathophysiology of syringomyelia associated with Chiari Ⅰ malformation of the cerebellar tonsils[J]. J Neurosurg, 1994, 80(1):3-15.
6. 伊卫宁, 游潮. 脊髓空洞症发病机制研究进展[J]. 中国现代神经疾病杂志, 2009, 2(9):117-119.
7. 王斌, 邱勇, 俞杨, 等. 青少年伴发脊柱侧凸的Chiari畸形的治疗策略[J]. 中华小儿外科杂志, 2004, 25(2):163-167.
8. Albert GW, Menezes AH, Hansen DR, et al. Chiari malformation Type I in children younger than age 6 years:presentation and surgical outcome[J]. J Neurosurg Pediatr, 2010, 5(6):554-561.
9. 陈春红, 吴沪生, 齐翔, 等. 儿童脊髓空洞症12例临床特征和诊断[J]. 中华儿科杂志, 2001, 33(8):497-498.
10. 焦颖, 李光乾. 小儿脊髓空洞症8例临床分析[J]. 中国实用神经疾病杂志, 2007, 10(1):101-102.
11. Mottolese C, Szathmari A, Simon E, et al. Treatment of Chiari type Ⅰ malformation in children:the experience of Lyon[J]. Neurol Sci, 2011, 32(11):S325-S330.
12. Tokunaga M, Minami S, Isobe K, et al. Natural history of scoliosis in children with syringomyelia[J]. J Bone Joint Surg Br, 2001, 83(3):371-376.
13. 郑冬凌, 郝彦峰, 吕茂利, 等. 小儿脊髓空洞症1例[J]. 实用医学杂志, 2007, 23(9):1417.
14. Durham SR, Fjeld-Olenec K. Comparison of posterior fossa decompression with and without dura plasty for the surgical treatment of Chiari malformation typeⅠin pediatric patients:a metaanalysis[J]. J Neurosurg Pediatr, 2008, 2(7):42-49.
15. Tao W, Zezhang Z, Jian J, et al. Syrinx resolution after posterior fossa decompression in patients with scoliosis secondary to Chiari malformation type Ⅰ[J]. Eur Spine J, 2012, 21(6):1143-1150.
16. Kan D, Yong-ning L, Gui-lin L, et al. Neural endoscopic assisted micro-invasive management of Chiari Ⅰ malformation[J]. Chin Med J, 2010, 123(14):1878-1883.
17. Krieger MD, Falkinstein, Bowen IE, et al. Scoliosis and Chiari malformation Type I in children[J]. J Neurosurg Pediatr, 2011, 7(1):25-29.
18. Galarza M, Sood S, Ham S. Relevance of surgical strategies for the management of pediatric Chiari type Ⅰ malformation[J]. Childs Nerv Syst, 2007, 23(6):691-696.
19. Fenoy AJ, Menezes AH, Fenoy KA. Craniocervical junction fusions in patients with hindbrain herniation and syringohydromyelia[J]. J Neurosurg Spine, 2008, 9(7):1-9.
20. Junpeng M, Chao Y, Haifeng C, et al. Cerebellar tonsillectomy with suboccipital decompression and duraplasty by small incision for Chiari Ⅰ malformation (with syringomyelia):long term follow-up of 76 surgically treated cases[J]. Turk Neurosurg, 2012, 22(3):274-279.
21. Novegno F, Caldarelli M, Massa A, et al. The natural history of the Chiari TypeⅠ anomaly[J]. J Neurosurg Pediatr, 2008, 2(9):179-187.
22. Singhal A, Bowen-Robert T, Steinbok P, et al. Natural history of untreated syringomyelia in pediatric Patients[J]. Neurosurg Focus, 2011, 31(6):1-5.
23. Strahle J, Muraszko KM, Kapurch J, et al. Natural history of Chiari malformation Type Ⅰ following decision for conservative treatment[J]. J Neurosurg Pediatr, 2011, 8(8):214-221.

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小儿ChiariⅠ型畸形合并脊髓空洞症研究进展

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