• 1. The First Clinical Medical College of Lanzhou University, Lanzhou 730000, P. R. China;
  • 2. The First Hospital of Lanzhou University, Lanzhou 730000, P. R. China;
HANBiao, Email: hanbiao66@msn.com
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Objective To systematically review the impact of side-to-side esophagogastric anastomosis on postoperative anastomostic leak, fibrosis stricture and stroesophageal reflux. Methods We searched PubMed, EMbase, The Cochrane Library (Issue 4 2015), Web of Science, CNKI, CBM, Wanfang Database and VIP up to April 2015. Randomized controlled trials involving the complications after side-to-side esophagogastric anastomosis were included. Data were extracted and methodological quality was evaluated by two reviewers independently with a designed extraction form. Then RevMan 5.3 software was used for meta-analysis. Results A total of 7 studies involving 684 patients were included. The results of meta-analysis showed that comparing with traditional anastomosis, side-to-side esophagogastric anastomosis could reduce the incidence of fibrosis stricture with RR=0.20 and 95% CI 0.11 to 0.36 (P<0.000 01). There was no statistical difference in incidence of postoperative anasotmostic leaks with RR=0.71 and 95% CI 0.43 to 1.19 (P=0.19) or stroesophageal reflux with RR=0.74 and 95% CI 0.50 to 1.11 (P=0.15) between the two groups. Conclusion Comparing with traditional anastomosis, side-to-side esophagogastric anastomosis could reduce the incidences of fibrosis stricture, but there is no statistical difference in anastomostic leak or stroesophageal reflux.

Citation: HUWen-teng, CAIQian-qian, LINRui-jiang, MAMin-jie, WEINing, ZHANGYu, YANGKan, HANBiao. Complications in Patients after Side-to-side Esophagogastric Anastomosis: A Systematic Review and Meta-analysis. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2016, 23(3): 224-229. doi: 10.7507/1007-4848.20160054 Copy

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