YI Kang 1,2 , HE Shao'e 2,3 , YOU Tao 1,2 , HOU Xiaodong 1,2 , XU Jianguo 2,4 , WANG Dan 2,4 , GAO Jie 2,4 , XU Xiaomin 2,4
  • 1. Department of Cardiovascular Surgery, The People’s Hospital of Gansu Province, Lanzhou, 730000, P.R.China;
  • 2. International Cooperation Base of Congenital Heart Disease Diagnosis and Treatment in Gansu Province, Lanzhou, 730000, P.R.China;
  • 3. The Second School of Clinical Medicine of Lanzhou University, Lanzhou, 730000, P.R.China;
  • 4. The First School of Clinical Medicine of Lanzhou University, Lanzhou, 730000, P.R.China;
YOU Tao, Email: syxzwk@126.com
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Objective To compare the efficacy of percutaneous closure guided by transthoracic echocardiography or angiography in the treatment of patent ductus arteriosus (PDA).Methods Literature databases such as CNKI, VIP, Wanfang Database, PubMed, Cochrane Library were searched for collecting published literatures on percutaneous closure for PDA guided by transthoracic echocardiography and angiography, retrieval time limit was up to April 2019. Two evaluators independently screened the literature, extracted the data and evaluated the quality according to inclusion and exclusion criteria. The collected data were analyzed by RevMan 5.3 software.Results Eight studies were included finally, with a total sample size of 681 cases. Meta-analysis showed that there was no statistical difference in the operative success rate between the echocardiography group and the angiography group (RR=0.99, 95%CI 0.97- 1.01, P=0.40). Postoperative complications were less in the echocardiography group than those in the angiography group (RR=0.26, 95%CI 0.11-0.59, P=0.001).The operation time (P<0.000 01), amount of intraoperative radiation (P<0.000 01), exposure time (P<0.000 01), hospitalization days (P<0.000 01) and hospitalization costs (P<0.000 01) in the echocardiography group were less or shorter than those in the angiography group, and the difference was statistically different.Conclusion Compared with angiography-guided, transthoracic echocardiography-guided percutaneous closure for PDA is a safe and effective method with less trauma, lower cost, and can replace angiography as one of the guiding methods for PDA.

Citation: YI Kang, HE Shao'e, YOU Tao, HOU Xiaodong, XU Jianguo, WANG Dan, GAO Jie, XU Xiaomin. Percutaneous closure of patent ductus arteriosus guided by transthoracic echocardiography or angiography: A systematic review and meta-analysis. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2020, 27(2): 199-205. doi: 10.7507/1007-4848.201908039 Copy

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