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find Keyword " Wnt pathway" 1 results
  • Effect of Secreted Frizzled-related Protein 2 and Wnt Signaling Pathway in Myocardial Regeneration Treatment

    Abstract: Stem cell paracrine has been considered as the main mechanism to promote infarcted myocardium regeneration and repair of damaged cardiomyocytes. With further research, secreted frizzled-related protein 2 (Sfrp 2) and stem cell paracrine are closely linked to each other. Sfrp 2 can competitively bind to the specific receptor Fz in Wnt signaling pathway, inhibit Wnt signaling pathway to regulates apoptosis, differentiation, and other life processes of stem cells, and therefore becomes a research hotspot in recent years. This review focuses on the mechanism of Sfrp 2/Wnt signal way in stem cell therapy for myocardial infarction.

    Release date:2016-08-30 05:50 Export PDF Favorites Scan
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