目的总结左胸骨旁小切口微创封堵分流方向偏向流出道的室间隔缺损(VSD)的初步经验。 方法2014年2~8月广州医科大学附属第一医院对15例分流方向偏向流出道的VSD患者施行左胸骨旁小切口微创封堵手术,其中男7例,女8例;年龄10个月~19岁(4.5±4.6)岁;体重5.5~54.0(14.6±14.1)kg;其中干下型6例,嵴内型6例,膜周部型3例;缺损直径2.5~6.5(4.0±1.2)mm,距主动脉瓣环距离≤1 mm 9例,≤2 mm4例,>2 mm 2例;合并主动脉瓣右冠瓣轻度脱垂5例;采用左胸骨旁第2或第3肋间1.5~2.5 cm切口,在经食管超声心动图(TEE)监视下在右心室流出道表面选择适当的穿刺点,建立VSD输送轨道并置入封堵器,观察有无残余分流、主动脉瓣反流;术后3个月复查经胸超声心动图。 结果15例均成功封堵,无中转开胸,无残余分流和心律失常,新发主动脉瓣轻微反流2例,围手术期输血1例;手术时间30~120(58±28)min,术中出血量5~200(26±50)ml;术后住院时间3~13(4.3±2.6)d,无二次开胸止血、Ⅲ°房室传导阻滞、主动脉瓣反流加重、溶血、切口感染等并发症;术后3个月返院复查经胸超声心动图13例,无新发主动脉瓣反流和封堵器脱落;2例术中新发主动脉瓣反流加重,其中1例出现残余分流。 结论左胸骨旁小切口封堵分流方向偏向流出道VSD 手术安全、切口小、操作简单,近期效果尚满意;对合并主动脉瓣轻度脱垂VSD 需慎重施行外科微创封堵手术。
Objective To investigate surgical strategy for the treatment of muscular ventricular septal defect (MVSD) in infants with multiple ventricular septal defects(VSD). Methods Clinical data of 46 infants with multiple VSD who underwent surgical repair in Shanghai Children’s Medical Center from January 2010 to April 2012 were retrospectively analyzed. There were 24 males and 22 females with their age of 8±6 months and body weight of 6.1±1.9 kg. All the patients received one-stage surgical repair,among whom MVSD of 10 patients was not found and repaired during the surgery. MVSD was repaired by surgical suture in 19 patients,hybrid repair under direct vision in 12 patients,and hybrid repair via the right ventricle in 5 patients. All the patients were regularly followed up after discharge by chest X-ray,ECG and color Doppler echocardiography to observe the closure of MVSD and the presence of residual shunt. Results All the 46 patients with multiple VSD survived their surgery without perioperative death. Three patients undergoing hybrid repair under direct vision received delayed sternal closure. One patient undergoing hybrid repair under direct vision had postoperative cardiac dysfunction. All the 46 patients were followed up for 1-17 months. Twenty-three patients had residual shunt of varying degrees during follow-up,and most of the MVSD of patients with residual shunt were <4 mm,who were receiving further follow-up and evaluation. Conclusion Appropriate surgical strategies can be applied according to specific surgical views during the operation for the treatment of MVSD in infants with multiple VSD,and satisfactory clinical outcomes can be achieved.
Objective To compare surgical results between real-time three dimensional echocardiography(RT-3DE) guided closure of atrial septal defect (ASD) through a right minithoracotomy and traditional surgical repair under cardiopulmonary bypass (CPB). Methods Sixty-four patients with secundum ASD received surgical repair in the First People’s Hospital of Honghe Autonomous Prefecture from April 2009 to April 2012. According to different surgical approach, all the patients were divided into group A and B. In group A, 35 patients underwent traditional ASD repair under CPB including 20males and 15 females with their age of 12-56 (16.4±4.0) years. In group B, 29 patients received real-time RT-3DE guidedASD closure through a right minithoracotomy without CPB, including 20 males and 15 females with their age of 15-50 (18.5±0.2) years. Operation time,postoperative mechanical ventilation time,hospital stay,chest drainage,mortality,morbidity and follow-up outcomes were compared between the 2 groups. Results Operation time (110.47±35.90 minutesvs. 159.32±20.60 minutes),postoperative mechanical ventilation time (10.40±22.30 hours vs. 16.40±12.20 hours),chestdrainage (106.71±85.20 ml vs. 146.70±75.63 ml)and postoperative hospital stay (4.0±1.0 days vs. 7.0±1.0 days)ofgroup B were significantly shorter or less than those of group A. In group A, 1 patient died postoperatively and 7 patientshad postoperative complications. In group B, there was no in-hospital mortality and 3 patients had postoperative complications.Postoperative morbidity of group A was significantly higher than that of group B (20.0% vs. 10.3%,P<0.05) . ConclusionFor ASD patients with definite surgical indications,RT-3DE guided ASD closure through a right minithoracotomy has more advantages over traditional surgical repair under CBP.
Abstract: Objective To investigate videoassisted thoracoscopic surgery (VATS) and percutaneous catheter occlusion (PCO) in interruption of patent ductus arteriosus (PDA), in order to achieve minimally invasive surgical injuries and better clinical results. Methods From November 1995 to September 2009, 312 cases of PDA were treated in Fujian provincial hospital, among whom 252 patients were interrupted with VATS(VATS group) and 60 patients with PCO technique(PCO group). For the VATS group, there were 78 males and 174 females aged from 7 d to 31 years old (9.16±8.91 years), while there were 17 males and 43 females aged from 4 to 57 years old (25.55±14.10 years) in the PCO group. We used titanium clip to interrupt PDA under videoassisted thoracoscope for patients in the VATS group, and adopted Amplatzer method for patients in the PCO group. The clinical results, complications and hospital cost in the two groups were compared in this study. Results In the VATS group, all the PDA were successfully interrupted with no residual shunt. In the PCO group, 5% (3/60) of the patients had minor residual shunt after the procedure. No mortality occurred in both groups. Time of the procedure and hospital stay in the PCO group were shorter than that in the VATS group (70.20±31.20 min vs. 112.50±16.30 min, t=6.344,P=0.002; and 4.70±2.20 d vs. 6.50±2.80 d, t=3.241, P=0.022, respectively). However, the hospital cost for each patient in the PCO group was much higher than that in the VATS group (23 222.00±4 333.40 yuan RMB vs. 8 904.50±2 634.60 yuan RMB,t=25.360, P=0.000). Conclusion Compared with PCO, VATS in interrupting PDA can achieved not only excellent clinical results, especially in the newborn and baby cases, but also very satisfying cost which is just a little more than one third of the PCO cost.
Abstract: Objective To introduce a new technique: transthoracic closure of perimembranous ventricular septal defect (VSD) without cardiopulmonary bypass (CPB) under transesophageal echocardiography (TEE)guidance, and summarize the clinical experiences and midterm followup results. Methods A total of 136 patients with perimembranous VSD, 3 months to 15 years averaging 1.8 years, underwent transthoracic device closure. The weight of these patients ranged from 4.0 to 26.0 kg with an average weight of 12.7 kg. The diameter of their VSD ranged from 3 to 12 mm averaging 5.1 mm. A small transthoracic incision (34 cm incision by inferior sternotomy or 23 cm transverse incision in the third intercostal space) was made and the best location for right ventricular puncture was chosen and the delivery pathway was established under TEE guidance. Proper devices were delivered and then deployed to close the defect. Patients were followed up closely with a standard protocol, arranged for echocardiography, electrocardiogram and chest Xray film. Results In all the cases, 131 cases of VSD (96.3%) were successfully closed. The procedure time was less than 90 minutes and the implanting time was 5.42 minutes (16.3±5.7 min). Symmetrical devices were implanted into 89(67.9%) of the 131 patients and the other 42 patients (32.1%) were closed with asymmetrical ones. The result of TEE soon after operation showed that 3 patients had tiny residual shunt, 4 had new trivial and mild tricuspid regurgitation (TR). However, no TR worsening, aortic regurgitation (AR), complete atrioventricular heart block, or left or right outflow tract obstruction was detected in all patients. One patient 〖CM(159mm〗with transient atrioventricular block restored to sinus rhythm after 3 days of medical treatment. Five cases (3.7%) were converted to conventional open heart repair during the operation. Followup was done to all the patients for a period ranged from 6 months to 30 months (18.3±6.6 months). Tiny residual shunt in the 3 cases mentioned above vanished during the followup period. No new TR, AR, hemolysis, thrombosis, dislocation of the devices, or outflow stenosis was detected postoperatively. The tiny incision caused less psychologic depression. Conclusion Minimally invasive transthoracic device closure of VSD without CPB is a simple, effective and safe intervention under guidance of TEE for most of perimembranous VSD patients. The short and midterm clinical outcomes are promising. Longterm followup is indispensable.