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find Author "常红" 5 results
  • Hepatosplenic γδ T-cell Lymphoma:Report on A Series of 2 Patients and Correlative Literature Review

    目的:探讨肝脾γδT细胞淋巴瘤的临床表现、病理学特征、免疫表型特点。方法:对我院2例确诊的肝脾γδT细胞淋巴瘤患者的临床资料进行分析、追踪随访并进行文献复习。 结果:该组患者均为青年男性,肝脾不同程度长大,发热,全血细胞减少(1/2),肝功能受损,淋巴结未受累;病理示瘤细胞弥漫性肝、骨髓的窦内侵犯;免疫表型:患者瘤细胞表达CD2(+)、CD3(+)、CD56(+)、CD16(+)、CD20()、TIA1(+)、TCRγ/δ(+)。结论:肝脾γδT细胞淋巴瘤是较为罕见的外周T细胞淋巴瘤,以肝脾长大、发热为主要临床表现,通常淋巴结不受累,病情进展快,疗效差,生存期短。

    Release date:2016-09-08 09:54 Export PDF Favorites Scan
  • 朗格汉斯细胞组织细胞增生症漏诊一例

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  • Clinical Features And Prognosis of Acute Myeloid Leukemia with Chromosome 8 and 21 Translocation

    【摘要】 目的 探讨t(8;21)急性髓系白血病(acute myeloid leukemia,AML)的临床特点及预后,提高对t(8;21)AML的认识。 方法 2010年5月收治1例t(8;21)AML患者,对其临床资料并复习相关文献进行分析。患者因乏力、皮下瘀斑入院,查体发现患者有胸骨压痛,脾肋下3 cm触及,血常规:白细胞80.37×109/L,异常细胞 23%,取患者骨髓液行形态学、流式细胞术检测及染色体核型检测。 结果 患者诊断为急性粒细胞白血病部分分化型(AML-M2b),AML1/ETO融合基因阳性,染色体核型分析t(8;21)(q22;q22)。 结论 t(8;21)AML是一类较为特殊的急性髓系白血病,在诊断时需寻找疾病的预后因素并进行分层,实施个体化治疗。【Abstract】 Objective To obsrve the clinical features and prognosis of acute myeloid leukemia (AML) with t(8;21). Methods The clinical data of one patient with t (8; 21) AML diagnosed in May 2010 was retrospectively analyzed. The chief complaints of the patient were malaise and ecchymosis. The physical examinations revealed sternum pain and splenomegaly; blood routine examination showed that the peripheral WBC count was 80.37×109/L, and the abnormal cells were 23%. Bone marrow samples were collected to perform the morphologic test, flow cytometry analysis and chromosome analysis. Results The patient was diagnosed as AML with maturation (AML-M2) with positive AML1/ETO fusion gene and translocation (8; 21) (q22; q22). Conclusion AML with t (8; 21) is different with other types of AML; patients with AML with t (8; 21) need individualized treatment.

    Release date:2016-09-08 09:52 Export PDF Favorites Scan
  • Repair of digital volar complex soft tissue defect with heterodigital antegrade digital artery island flap innervated by digital nerve

    Objective To investigate the effectiveness of heterodigital antegrade digital artery island flap innervated by proper digital nerve and the dorsal branch of proper digital nerve for repairing digital volar complex soft tissue defects. Methods Between May 2014 and January 2018, 27 patients with digital volar complex soft tissue defects were treated. There were 17 males and 10 females with an average age of 37 years (range, 18-60 years). The causes included electric saw injury in 8 cases, twisted injury in 12 cases, and heavy pound injury in 7 case. There were 9 thumbs, 5 index fingers, 6 middle fingers, 3 ring fingers, and 4 little fingers. The interval between injury and admission ranged from 1 to 4 hours (mean, 2.5 hours). The defect size ranged from 2.2 cm×1.4 cm to 3.8 cm×2.3 cm. The mean length of unilateral proper digital nerve defect was 2.9 cm (range, 2-4 cm). All defects were repaired with heterodigital antegrade digital artery island flap innervated by the proper digital nerve and the dorsal branch of the proper digital nerve. The proper digital nerve and the dorsal branch of the proper digital nerve in the flap were anastomosed with the proper digital nerve stumps in the wound. The flap size ranged from 2.4 cm×1.6 cm to 4.1 cm×2.6 cm. A segment of dorsal branch of the proper digital nerve was intercalated into the defect of the proper digital nerve in donor site. And the defect of donor site was repaired with the full-thickness skin graft. Results All flaps and skin grafts survived, and the wounds healed by first intention. All patients were followed up 12-24 months (mean, 17 months). The appearance, color, and texture of the flaps were similar to the surrounding tissue. There was no pain and double sensibility in any flap. At last follow-up, the static two-point discrimination of the flaps ranged from 4 to 8 mm (mean, 5.3 mm). And the two-point discrimination of digital pulps of recipient and donor fingers ranged from 4 to 10 mm with the average of 6.2 mm and 6.0 mm, respectively. According to the functional assessment criteria of the upper limb formulated by the Hand Surgery Society of the Chinese Medical Association, the results were excellent in 18 cases and good in 9 cases. No scar contracture was observed in donor site. Conclusion The heterodigital antegrade digital artery island flap innervated by the proper digital nerve and the dorsal branch of the proper digital nerve provides a safe and simple technique with minimal donor site cost and satisfactory effectiveness, which could be an ideal option for repairing digital volar defect, especially for the defect complicated with digital nerve defect.

    Release date:2019-11-21 03:35 Export PDF Favorites Scan
  • 同指指动脉背侧皮支血管链皮瓣逆行修复手指指端脱套伤

    目的探讨同指指动脉背侧皮支血管链皮瓣逆行修复手指指端脱套伤的疗效。方法2015 年 9 月—2017 年 2 月,收治 25 例(25 指)第 2~5 指指端脱套伤患者。男 16 例,女 9 例;年龄 20~63 岁,平均 38 岁。致伤原因:机器绞伤 12 例,挤压伤 8 例,重物砸伤 5 例。受伤至手术时间为 2.0~5.5 h,平均 4.0 h。指端创面范围为 2.0 cm×1.8 cm~4.0 cm×2.3 cm。采用大小为 2.2 cm×2.0 cm~4.4 cm×2.5 cm 的同指指动脉背侧皮支血管链皮瓣修复创面,皮瓣携带的指固有神经背侧支及指背神经与创面内双侧指固有神经残端吻合。供区游离植皮。结果术后 2 例皮瓣出现静脉回流障碍,对症处理后成活;其余皮瓣以及全部供区植皮均顺利成活。患者均获随访,随访时间 10~18 个月,平均 15 个月。皮瓣外形、颜色、质地良好,末次随访时皮瓣静态两点辨别觉为 5~9 mm,平均 6.9 mm。伤指功能参照中华医学会手外科学会上肢部分功能评定试用标准,获优 17 例、良 7 例、可 1 例。结论采用同指指动脉背侧皮支血管链皮瓣逆行修复指端脱套伤,操作简便、供区损伤小,疗效满意。

    Release date:2020-06-15 02:43 Export PDF Favorites Scan
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