腹股沟疝是外科常见病及多发病,尤其多见于老年患者。据美国健康中心资料,美国每年因疝手术住院患者约68万人,其中1/3(34%)是65岁以上的老年人[1]。我国老龄人口众多,不但老年疝的发病率高过西方国家,而且传统疝修补术后造成的高复发率也很突出,因此,探索老年腹股沟疝的治疗是当今外科所关注的一个热点问题。
目的 探讨严重肝损伤的有效治疗方法。方法 回顾性分析我院1996~2002年期间43例严重肝损伤患者的外科治疗方法。结果 术后治愈32例(74.4%),死亡11例(25.6%),其中10例死于失血性休克、多脏器功能衰竭,1例死于术后急性大出血、心跳骤停,术后9例发生并发症。结论 外伤性肝损伤应及时手术止血,同时对严重的合并伤进行处置,手术方式应根据伤者具体情况作出正确选择。
Objective To explore the clinical value of early enteral nutrition in severe acute pancreatitis (SAP) by percutaneous endoscopic gastrostomy/jejunostomy (PEG/J).Methods Treatment condition of nighty patients with SAP were retrospectively analysed.The 90 patients were collected peripheral venous blood respectively on 1, 12, and 18 d after admission to hospital.Forty-five of them were in PEG/J group, the others were in control group. Serum IL-6,TNF-α and endotoxin were detected by enzyme-linked immunosorbent assay (ELISA),CD4 /CD8 was determinated by indirect immunofluorescence staining method (FITC-labeled).Results On 12 d and 18 d,the levels of serum IL-6, TNF-α, and endotoxin in PEG/J group were lower than those in control group (P<0.01).The CD4 /CD8 was significantly higher than that in control group (P<0.01).In control group, 2 cases complicated upper gastrointestinal haemorrhage,4 cases complicated pancreatic pseudocysts, and 2 cases complicated double infection, the temperature became normal after about 13.5 d.In PEG/J group, there were not upper gastrointestinal haemorrhage and double infection,but 2 cases also complicated pancreatic pseudocysts, the temperature became normal after about 10.5 d.Conclusion The clinical effectiveness of early enteral nutrition in SAP by PEG/J is satisfactory.
目的 探讨腹腔镜脾切除术治疗遗传性球形红细胞增多症的可行性、手术技巧及效果评价。方法 收集我科2006年1月至2008年1月收治的行腹腔镜脾切除术治疗的遗传性球形红细胞增多症患者18例的临床资料进行回顾性分析。结果 所有患者均顺利完成腹腔镜脾切除术。术中出血50~600 ml,平均200 ml。手术时间50~150 min,平均136 min(包括胆囊切除时间)。术后住院时间5~10 d,平均7.8 d,所有患者住院期间无暴发感染、胰漏等并发症发生。术后随访4~12个月,平均6.7个月,术前症状完全消失。结论 腹腔镜脾切除术是治疗遗传性球形红细胞增多症的一种安全有效的方法。
【Abstract】ObjectiveTo investigate the effects of high molecular bio-degradable film on preventing peritoneal adhesion. MethodsOne hundred and twenty rats were divided into control group, non-bio-degradable film group and polycaprolactone (PCL) group. Animal models of peritoneal adhesion made by operations on rats serve as control group. In the study, non-bio-degradable film and biodegradable, namely PCL films sensitive to pseudomonas enzyme, were put into the opening of peritoneum. The effect of the films on peritoneal adhesion was examined on 1, 3, 7 and 30 d after operation. ResultsPeritoneal adhesion was found in all the rats of control group and very low in PCL group and non-bio-degradable film group. ConclusionPCL film can effectively prevent the formation of postoperative peritoneal adhesion.