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find Author "江军" 4 results
  • Bias Control of Systematic Reviews

    The most important difference between systematic review and traditional narrative review lies in their respective quality, namely the degree of bias control. Generally speaking, the sources of bias include the process of literature searching, study selection, data extraction and original studies. A systematic review may greatly reduce bias, as it takes effective steps such as developing search strategies, undertaking funnel plot analysis, using established criteria for study selection, and assessment of the methodology quality of studies. All these help to control, identify and, describe the possible bias.

    Release date:2016-09-07 02:27 Export PDF Favorites Scan
  • 新生儿脑电图-睡眠分期及其应用

    近年来新生儿脑电图(EEG)对于评估脑功能的作用被逐渐认可,并在国内越来越多的医院开展,一般结果由医师阅图后凭经验主观判断,仅依靠定性EEG。而随着定量EEG研究的增多,依靠客观数据处理实现新生儿睡眠自动分期得以实现,并可以自动检出新生儿癫痫发作的时间段,节省人工阅图时间,辅助医师对结果做出判断。EEG-睡眠分期的分析应用广泛, 可以帮助更准确的识别新生儿脑病,评估新生儿神经功能和脑成熟度,提供一种研究新生儿大脑发育成熟的机制的方法。

    Release date:2017-11-27 02:36 Export PDF Favorites Scan
  • 一例儿童亚急性硬化性全脑炎的脑电演变及临床特点

    Release date:2023-05-04 04:20 Export PDF Favorites Scan
  • Roles of Hippocampal long-term potentiation in chronic cognitive dysfunction of immature epileptic rats

    ObjectiveTo investigate the effects of hippocampal long-term potentiation (LTP) on cognitive dysfunction in immature epileptic rats. MethodsImmature epileptic rats were established by intraperitoneal injection of lithium chloride-pilocarpine (li-pilo). Racine classification standard modified by Becker was used to evaluate behavior of epileptic seizure, and the survival rats within RacineⅣmagnitude were selected in the experiment. The function of learning and memory of epileptic rats when they were adult was assessed using Morris water maze experiment, and their independent exploratory behavior was evaluated by the open-field test. Field potential was recorded by electrophysiological technology to detecte whether hippocampal LTP was essential of cognitive dysfunction. ResultsThe function of learning and memory was significantly impaired when compared with controls(n=8, t=10.86, P < 0.05;n=8, t=9.98, P < 0.05). In addition, independent exploratory behavior was significantly reduced when compared with controls(n=8, t=12.89, P < 0.05). Besides, CA1 hippocampal LTP induced by high-frequency stimulation presented the significant inhibition in epileptic rats with cognitive dysfunction when compared with controls(Slope:n=8, t=13.32, P < 0.05;Amplitude:n=8, t=20.02, P < 0.05). ConclusionInhibition of CA1 hippocampal LTP may be implicated in cognitive dysfunction of epileptic rats.

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