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find Keyword "深吸气量" 3 results
  • Relationship between the Inspiratory Capacity and Clinical Characters of Stable Chronic Obstructive Pulmonary Disease

    【摘要】 目的 探讨深吸气量(inspiratory capacity,IC)与慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者临床特征的相关性。 方法 2009年12月-2010年6月纳入84例稳定期COPD患者,测定6分钟步行试验(6-minute walk test,6MWT)、圣乔治生活问卷评分(St George′s respiratory questionnaire,SGRQ)及肺功能检查:第1秒用力呼气容积(forced expirotovy volume in one second,FEV1)、IC、IC与肺总量(total lung capacity,TLC)比值(IC/TLC)等相关指标,并进行相关性分析。 结果 6MWT值与FEV1无明显直线相关(r=0.14,Pgt;0.1);6MWT值与FEV1≥60%无明显直线相关(r=0.16,Pgt;0.1);6MWT值与IC值呈正的直线相关(r=0.317,Plt;0.01);6MWT值与IC/TLC值呈正的直线相关(r=0.274,Plt;0.01);SGRQ值与FEV1呈负的直线相关(r=-0.307,Plt;0.01);SGRQ值与IC值无直线相关(r=-0.001,Pgt;0.25);SGRQ值与IC/TLC值无直线相关(r=-0.003,Pgt;0.25)。 结论 对COPD患者,IC比FEV1更准确地反映患者的运动耐量的程度,FEV1比IC更准确地反映患者呼吸困难的严重程度。【Abstract】 Objective To explore the relationship between the inspiratory capacity (IC) and clinical characters of stable chronic obstructive pulmonary disease (COPD). Methods Between December 2009 and June 2010, 84 patients with stable COPD were enrolled. Lung function (FEV1, IC, IC/TLC) ,6 minute walk-test (6MWT) and St George′s respiratory questionnaire (SGRQ) were examined. The relationship among FEV1, IC, IC/TLC, and the results of 6MWT and SGRQ by Pearson correlation analysis. Results There was no linear correlation between 6MWT and FEV1 (r=0.14,Pgt;0.1), and 6MWT and FEV1≥60% (r=0.16,Pgt;0.1). There was positive correlation between 6MWT and IC (r=0.317,Plt;0.01), and 6MWT and IC/TLC (r=0.274,Plt;0.01). There was negative correlation between SGRQ and FEV1 (r=-0.307,Plt;0.01); and no linear correlation between SGRQ and IC (r=-0.001,Pgt;0.25), and SGRQ and IC/TLC (r=-0.003,Pgt;0.25).  Conclusion In stable COPD patients, IC may be more accurate than FEV1 in refection of exercise tolerance while FEV1 may be more sensitive than IC in evaluation of dyspnea.

    Release date:2016-08-26 02:18 Export PDF Favorites Scan
  • 深吸气量的意义及其在慢性阻塞性肺疾病评估中的价值

    慢性阻塞性肺病( COPD) 是一组慢性进行性的呼吸系统疾病, 以不完全可逆性气流受限为特征。CPD 全球创议( GOLD) 标准强调了肺功能检查对COPD 的诊断价值, 其中第1 秒用力呼气容积/ 用力肺活量( FEV1 /FVC) 和FEV1 占预计值的百分比分别作为判断气流阻塞存在和阻塞程度的指标, 但有研究结果显示: 患者的呼吸困难程度、运动能力与这两个参数的相关性较差, 与肺容积参数---深吸气量( inspiratory capacity, IC) 反而有较好的一致性, 从而导致临床上经常用FEV1 进行病情严重度分级、用IC 评估治疗效果的不一致现象, 这与其他气道疾病有明显的不同。......

    Release date:2016-09-13 03:50 Export PDF Favorites Scan
  • Predictive value of inspiratory capacity and total lung capacity on acute exacerbation of chronic obstructive pulmonary disease

    Objective To study the predictive value of inspiratory capacity (IC) and total lung capacity (TLC) on acute exacerbation of patients with chronic obstructive pulmonary disease (COPD). Methods The in-patients due to acute exacerbation of COPD (AECOPD) from February 2017 to March 2019 were recruited in the study. Research data were collected during the recovery period and one year follow-up , and the patients were divided into two groups according to whether there was another acute exacerbation. Results A total of 372 patients were included in the study. In the patients with acute exacerbation, the age and TLC as a percentage of the expected value (TLC%pred) were higher, while IC as a percentage of the expected value (IC%pred) and the ratio of IC and TLC (IC/TLC) were lower. Univariate analysis revealed that IC/TLC≤25% was a significant predictor of acute exacerbation (P<0.001) after the AECOPD patients were discharged. Multivariable analysis revealed age (OR=1.25, 95%CI 1.17 to 1.44, P<0.001) and IC/TLC≤25% (OR=1.68, 95%CI 1.36 to 2.07, P<0.001) were independent risk factors of AECOPD.Conclusions Decreased IC/TLC significantly correlates with poor prognosis of COPD. IC/TLC≤25% is an independent risk factor for acute exacerbation.

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