ObjectiveTo investigate the status of newly diagnosed adult epilepsy in the General Hospital of Jilin Province, in order to improve the prevention and treatment of epilepsy. MethodsTo collect the clinical data of newly diagnosed adult epilepsy from October 2016 to February 2017, and to follow up 6 months. ResultsA total of 81 patients were included. At the last clinic visit, 73 cases origined from focal, 74 cases were positive in EEG examination, 56 cases were unknown etiology, 12 cases had hippocampal sclerosis, 48 cases were mildly declined cognitive function, and 30 cases were poor compliance. ConclusionThe newly diagnosed epilepsy were focal origin, delayed treatment, mildly declined cognitive function and poor compliance.
ObjectAimed to describe the clinical characteristics of the patients with interictal schizophrenia-like psychoses of epilepsy (SLPE), so as to improve the identification, diagnosis and treatment.MethodsWe collected the cases from January 2017 to December 2019 that diagnosed as "epileptic psychosis/organic mental disorders/brain damage and functional disorders and somatic diseases caused by other mental disorders/organic delusions (schizophrenia-like) disorders" in the medical record system of the Sixth Hospital of Changchun. The discharge records were re-diagnosed by two experienced epilepsy specialists and psychiatrists respectively. Retrospective statistical analysis was performed on the cases identified as SLPE.ResultsA total of 45 patients were diagnosed as SLPE (male: female=1:1.4). The onset age of epilepsy and mental symptoms was (16.4±12.5) years and (35.3±13.4) years respectively. The duration of mental symptoms after first seizure was (18.9±13.4) years. 7 patients (15.6%) were not treated with AEDs, and 26 patients (57.8%) were treated with first generation AEDs. 8 patients (17.8%) had no seizures within 1 year before the onset of mental symptoms, and 28 patients (62.2%) had frequent seizures, even status epilepticus or clustered seizures. 2 patients (4.4%) had generalized tonic-clonic seizure, only 4 patients (8.9%) showed focal impaired awareness seizure, and 39 patients (86.7%) had focal to bilateral tonic-clonic seizure.The PANSS positive symptom score, PANSS negative symptom score and BPRS score were (15.1±4.4), (17.7±4.6) and (44.7±8.4) respectively.ConclusionThere were some features of epilepsy in SLPE, such as early onset age, frequent seizure (some patients were seizure-free), focal epilepsy, and poor AEDs treatment compliance. The onset age of mental symptoms in SLPE was later than Schizophrenia and long duration after first seizure. The PANSS scale showed that the mental symptoms of patients with SLPE were similar to those of patients with schizophrenia, and both positive and negative symptoms existed.
ObjectiveTo investigate clinical features and progress in women with catamenial epilepsy. MethodsThe data obtained from retrospective study in 20 patients with catamenial epilepsy and reviewing published study of catamenial epilepsy. ResultsSeizures of all cases were relatived with the menstrual cycle. Seizures that only occured perimenstrually in 7 cases, 13 cases experienced exacerbation during this time. Only 2 of the 20 cases pointed to generalized sizures.12 of 18 cases which were partial seizures identified with complex partial seizures. Of 17 patients who had EEG results, 1 showed mild abnormal waves, 1 showed slow waves, 1 showed sharp waves, 1 showed spike and slow wave complex, 2 showed generalized polyspike and slow wave complex, 11 showed focal sharp waves,spike waves and spike and slow wave complex. All patients accepted 1 or more AEDs treatment.1 patient seizure free for 2 years after menopause, 2 cases of treatment were unclear, 5 cases had positive outcomes(4 cases seizure free for 1 and more years,1 case for 6 months), 12 cases were poorly controlled, especially 9 cases were refractory epilepsy. ConclusionIt is found that catamenial epilepsy more commonly in facal and the rate of refractory epilepsy is higher. Treatment of catamenial epilepsy power with more samples, multi-center clinical trials.