Silent brain infarct (SBI) is frequently identified after transcatheter aortic valve replacement (TAVR) when patients are screened with imaging examination. With the indication of TAVR extending to lower-risk and younger patients, attention should be paid to SBI that poses a potential long-term threat to the nervous system. This review expounds the basic information, risk factors, mechanism, possible outcomes, prognosis, and prevention of SBI, to provide a reference for the management of SBI after TAVR in clinical practice.