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find Keyword "局部复发" 19 results
  • Research Progress of Preoperative Radiotherapy for Rectal Cancer

    Objective To summarize the current advancement of preoperative radiotherapy for rectal cancer. Methods Relevant literatures about current advancement of preoperative radiotherapy for rectal cancer published domesticly and abroad recently were collected and reviewed. Results The lower local recurrence rate and longer disease-free survival time were observed in preoperative radiotherapy, compared with postoperative radiotherapy for rectal cancer. The recurrence rate was higher in short-course radiotherapy, compared with conventionally radiotherapy for stageⅢrectal cancer, but there was no significant difference for stageⅡrectal cancer. The biology molecular such as p53, CEA, Cox-2, EGFR, and VEGF had shown to be radiosensitive. Conclusions The proposal of preoperative radiotherapy for rectal cancer, could be prone to conventionally radiotherapy. There are more screening targets for preoperative radiotherapy in extensive exploration of diverse radiosensitivity. Biology molecular, developed gene expression profiling, and gene chips for rectal cancer may contribute to the individualization treatment.

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  • TOTAL MESORECTAL EXCISION FOR RECTAL CANCER

    Objective To introduce the surgical technique and results of total mesorectal excision (TME) for rectal cancer. Methods Reviews.Results As a result of TME, local recurrence rates have declined from 20%-30% to 3%-8%, 5-year survival rate have risen to 75%, and the rates of sphincter preservation have risen too.Conclusion Total mesorectal excision reduces the local recurrence rates and raise the survival figures after excision of rectal cancer. Patients have a high quality of life.

    Release date:2016-08-28 05:29 Export PDF Favorites Scan
  • 氟尿嘧啶缓释颗粒植入食管癌瘤床对食管癌根治术后局部复发的影响

    目的 观察氟尿嘧啶缓释颗粒瘤床植入对食管癌根治术后局部复发的疗效和预后影响。 方法 纳入2009年1~12月期间重庆三峡中心医院60例行食管癌根治术患者,按其治疗方法分为试验组和对照组两组,每组30例。试验组男24例、女6例,年龄(62.00±7.70)岁;对照组男23例、女7例,年龄(60.20±8.20)岁。试验组患者术中在瘤床植入氟尿嘧啶缓释颗粒300 mg,对照组不植入任何物质。比较两组患者临床结果差异。 结果 两组患者术后主要并发症发生率差异无统计学意义(P>0.05),试验组术后复发时间较对照组显著延长(P<0.05)、试验组术后复发病灶大小及复发病灶的个数较对照组显著减少(P<0.05);两组患者1年生存率差异无统计学意义,但试验组患者2年及3年生存率显著高于对照组(P<0.05),试验组中位生存时间较对照组显著延长[(29.2±1.9)月 vs. (23.4±1.4)月,P<0.05] 。 结论 食管癌术中瘤床植入氟尿嘧啶缓释颗粒能延缓肿瘤复发时间、提高食管癌患者2年及3年生存率,延长患者中位生存时间,而不增加术后并发症的发生,是一种安全、有效的局部化疗方法。

    Release date:2016-08-30 05:47 Export PDF Favorites Scan
  • 补充性全肺切除术治疗肺癌

    目的评估补充性全肺切除术的适应证、危险性和结果. 方法回顾性分析49例残肺恶性病变患者的补充性全肺切除术,其中第二原发性肺癌14例,肺癌复发35例;再次手术平均间隔期为29个月. 结果全组死亡6例,1例死于术中,5例死于术后,手术死亡率为12.24%.术后随访1个月~5年,中位数生存时间2.5年,5年生存率为33%. 结论补充性全肺切除术治疗残肺癌,手术死亡率和术后5年生存率接近标准的全肺切除术.

    Release date:2016-08-30 06:31 Export PDF Favorites Scan
  • Reoperation for Local Recurrence of Rectal Cancer(Analysis of 56 Cases)

    Objective To approach the surgical therapeutic efficacy of local recurrence of rectal cancer. Methods Fifty-six patients with local recurrence of rectal cancer suffered from reoperation from January 2003 to January2011 in this hospital were collected. Chi-square test was performed to analyze the complete excision rates of reoperation for different recurrent time after radical resection and different surgical procedures after primary radical resection of rectalcancer. The method of log-rank test was used for survival analysis of the Miles and Dixon procedure. Results ①The opera-tion time and intraoperative bleeding of reoperation for local recurrence of rectal cancer were more than those of the primary radical resection of rectal cancer (P<0.05). ②The complete resection rate of the local recurrence of rectal cancer in 5 years after primary radical resection of rectal cancer was higher than that of the local recurrence of rectal cancer within 2 years after primary radical resection of rectal cancer, and the difference was statistically significant (P<0.01). ③The complete resection rate of the local recurrence of rectal cancer of the technique of Dixon in the primary radical resection of rectal cancer was higher than that of Miles, and the difference was statistically significant (P<0.05). ④The median survival time and 2-year survival rate and 5-year survival rate of the technique of Dixon in the reoperation were longer or higher than those of Miles, and the differences were statistically significant (P<0.05). Conclusions Surgical procedure and postoperative recurrence time after primary operation can both influence complete excision rate of reoperation for local recurrence of rectal cancer. And reoperation for local recurrence of rectal cancer can prolong the survival time.

    Release date:2016-09-08 10:23 Export PDF Favorites Scan
  • Clinical Significance and Indication of Total Pelvic Exenteration for Local Recurrence of Rectal Cancer

    Release date:2016-09-08 10:23 Export PDF Favorites Scan
  • Current Status of Treatment and Progress of Radiotherapy for Local Recurrence of Rectal Cancer

    Release date:2016-09-08 10:23 Export PDF Favorites Scan
  • Progress of Multidisciplinary Modality in Diagnosis and Treatment for Local Recurrence of Rectal Cancer

    Release date:2016-09-08 10:23 Export PDF Favorites Scan
  • Current Status of Therapy for Local Recurrence of Rectal Cancer

    Release date:2016-09-08 10:23 Export PDF Favorites Scan
  • Computed Tomography and Magnetic Resonance Imaging in Diagnosis and Differential Diagnosis for Local Recurrence of Rectal Cancer

    Objective To investigate the situation and prospect of local recurrence of rectal cancer by using CT and MRI. Method Relevant references about the imaging diagnosis of local recurrence of rectal cancer, which were published domestic and abroad in recent years, were collected and reviewed. Results In the diagnosis of local recurrence of rectal cancer, the sensitivity of CT was higher than that of MRI, while the specificity and accuracy were not. Perfusion CT, dynamic contrast-enhanced MRI, and diffusion weighted imaging were valuable in diagnosing local recurrence of rectal cancer, as new diagnostic techniques. Conclusion Both CT and MRI are important and valuable methods in diagnosing for local recurrence of rectal cancer.

    Release date:2016-09-08 10:23 Export PDF Favorites Scan
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