It has always been an important policy of the Chinese government to provide aid and assistance for the development of Tibet. With nearly one-eighth of China’s total land areas and about 0.002% of China’s total population, the Tibet Autonomous Region lags behind the domestic average level in medical education and is in bad need for medical professionals. The West China Center of Medical Sciences (WCCMS) of Sichuan University has managed to introduce US projects to set up the West China–Tibet Telemedical Education System to transmit medical courses in a real-time and interactive way. Based on this system, WCCMS has established a model for assisting the Tibet University Medical College through transmitting medical courses, training their medical faculty, sending WCCMS faculty to work in Tibet and admitting medical teachers and students from Tibet to study and be trained at West China Medical School and Hospital.
Objectives Retrospective analysis of the Tibetan convulsive status epilepticus (CSE) for the aetiology, prognosis and its influencing factors in Tibet area. Methods Through electronic patient record, making “epilepsy”, “status epilepticus ”, “epileptic seizure” as keywords, convulsive status epilepticus patients in the People’s Hospital of Tibet Autonomous Region hospitalized from January 2015 to December 2020 were retrospectively observed, gathering their clinical data and aided examinations furthermore, and the prognoses were returned by telephone, meanwhile the functional status of those patients was assessed by the modified rankin scale. and the causes differ in gender, age, out-of-hospital antiepileptic treatment, family history of epilepsy and history of epilepsy were analyzed. The prognostic factors were analyzed by logistic regression. Results A total of 2 254 hospitalized patients with epilepsy were retrieved, including 331 CSE patients aged 14~84 years, 219 males and 112 females. There were 36 lost calls, 62 CSE deaths (21.01%), and 4 adverse outcomes (non-death)(1.7%).There were statistically significant differences in etiology of CSE in different ages and history of epilepsy (P<0.05), but there were no statistically significant differences in gender, out-of-hospital antiepileptic treatment, progression of refractory status epilepticus and family history of epilepsy. Cerebrovascular disease was the main cause of CSE in people aged 45 and over (54 cases), while the main cause of CSE in people aged under 45 was unknown (104 cases).Among the patients with previous history of epilepsy, the highest proportion was unknown cause [117 cases (48.8%)]; Among patients without a history of epilepsy, cerebrovascular disease [34 cases (37.4)] was the most common cause of CSE. Multivariate logistic regression analysis of prognostic factors of CSE showed that gender, age, GCS and electrolyte disorder had statistically significant effects on the death of CSE patients (P<0.05), while altitude and their duration and other factors had no statistically significant effects on the death of CSE patients (P>0.05). ConclusionsCerebrovascular disease is the leading cause of CSE in people aged 45 and over. Male, advanced age, low GCS score at discharge, and electrolyte disorder were risk factors.
ObjectiveTo analyze the clinical features of psychogenic non-epileptic seizures (Psychogenic nonepileptic seizures, PNES) in Tibetan population in Tibet, so as to help clinicians identify the disease.MethodsRetrospective analyzed the clinical data of patients with PNES in the Department of Neurology, People's Hospital of Tibet Autonomous Region from June 2016 to December 2018.ResultsIn general clinical data, there were significant differences between male and female patients in the results of video electroencephalogram (EEG) monitoring the non-epileptic seizures (P< 0.05). There were no significant differences in mean age, mean onset time, family history of epilepsy, head injury and marital status between male and female patients (P> 0.05). There was no significant difference in symptoms between male and female, but there were differences among different age groups (P> 0.05). In the onset age, the main manifestation was young women, but there was no significant difference in the onset of PNES among different age groups.ConclusionsThere was significant differences between male and female PNES petients, but no significant differences in onset time, marriage and family history of epilepsy between the male and female patients with PNES in Tibet. The clinical manifestations of PNES were different in different ages of patients in Tibet.
摘要:目的:探讨滋养叶细胞肿瘤的临床特征、治疗、预后。方法:回顾性分析我院1997年1月至2008年12月诊治的28例良、恶性滋养叶细胞肿瘤患者的临床资料。结果:28例中,侵蚀性葡萄胎1例,经化疗后已随访3年无复发征象;2例因“肺部转移”和“持续性葡萄胎”回内地治疗;5例尚在随访中,其余经随访已达临床治愈。结论:妊娠滋养叶细胞肿瘤患病率高;良性葡萄胎预后好,但应警惕其潜在恶变性,应早期发现,早期治疗,以减少其恶变带来的危害;恶性滋养叶细胞肿瘤经积极化学治疗后可达到根治。Abstract: Objective: To explore the clinical feature，treatment and prognosis of gestational trophoblastic tumor. Methods: Retrospectively analyzed the clinical pathological materials of 11 patients with carcinoid and malingnant gestational trophoblastic tumor treated from January.1997 from December 2008 in our hospital. Results: In the 28 cases,1 case of erosive hydatidiform mole did not relapse after the chemical treatment of 3 years’ survey; 2 cases went back to the inland due to “lung transference and continuous hydatidiform mole”; 5 cases was still in the followup survey; the last had been cured after followup survey. Conclusion: Gestational trophoblastic tumor have a higher rate or happening; The carcinoid tumor has a better prognosis, yet people should guard its initial bad change; malignant gestational trophoblastic tumor can be cured after the positive chemical treatment.
Tibetan population has been living in Tibet plateau for more than thousands of years ago. Although, the environment is unlikely to be an ideal place for residence. They have evolved genetical and physiological adaptions living in Tibetan highlands. In recent several years, foreign scientists have noticed that lung cancer mortality is reduced at high altitude. Many in vitro and in vivo experiments explored the mechanism of this phenomenon. In this review we discuss the lung cancer incidence and mortally of Tibetan population, as well as the possible underlying mechanism including oxygen level, radiation, inhalable particulate matter, metabolism, hypoxic induced factor pathway and immune system. But, the clinical data as well as basic researches of Tibetan population remain insufficient, which required further investigation.
West China Hospital of Sichuan University as a national-level regional medical center in the western part of the country, focused on the actual situation in Tibet and actively carried out precision health poverty alleviation work. Guided by " precision”, the hospital has built a close-knit medical association – Hospital of Tibet People’s Government in Chengdu Office, and through the comprehensive improvement of medical care, teaching, scientific research, and management, creates a medical and health service system with Tibet characteristics. Combining " blood transfusion” and " hematopoietic” to build a " West China Model” for precision health poverty alleviation, West China Hospital of Sichuan University fully demonstrates the public welfare and responsibility of a national-level regional medical center, and constantly exerts regional radiation and leading role, promotes the medical and health service system continuous improvement in Tibet.
ObjectiveTo investigate the situation of tuberculosis (TB) infection in primary and middle school students and to provide scientific basis for TB prevention and control in Nyingchi. MethodsPrimary and middle school students in Nyingchi were investigated from 2006 to 2008 using a questionnaire, and purified protein derivative (PPD) tests were carried out among the sampling students. Data analysis was conducted by SPSS 13.0. ResultsIn 3 987 included primary and middle students, the positive, strongly positive and overall positive rates of PPD were 11.4%, 5.1%, 16.5%, respectively. Five patients with TB were found in the investigation, and the prevalence was 125.4 per 100 000. The positive and strongly positive rates were 11.3% and 4.4% in male, 11.5% and 5.7% in female, respectively. The positive and strongly positive rates were 6.9% and 3.9% in primary school students, 18.8%, 7.1% in middle school students, respectively. Both the positive rate and strongly positive rate in middle school students were higher than those in primary school students (P < 0.05). The positive rates in town, village and floating population were 16.5%, 9.5%, 8.9%, respectively, and their strongly positive rates were 6.1%, 4.8%, 1.4%, respectively. Both the positive rate and strongly positive rate in town were higher than those in village and floating population (P < 0.05). The strongly positive rates in Tibetan, the Han nationality and other ethnic minorities were 5.2%, 4.0%, 6.0%, respectively. The strongly positive rates in Tibetan and other ethnic minorities were higher than those in the Han nationality (P < 0.05). ConclusionThe infection and prevalence rate of TB of primary and middle school students in Nyingchi are fairly high. TB prevention and control for the high-risk populations should be strengthened in primary and middle schools in Nyingchi.
ObjectiveTo compare whether the training process of commissioned training residents from Tibet and non-commissioned training residents have achieved homogenized.MethodsThe training time and operation frequency data of 170 commissioned training residents from Tibet and 96 non-commissioned training residents of grade 2016 during the 19 months from September 2016 to April 2018 were collected. The 25 operational data of 11 departments that are representative and comparable are compared.ResultsThe two types of trainees completed the rotation of 47 different departments within 19 months, of which 45 departments were the departments where both types of students were rotated. Among these 11 departments, the average training time of trainees from Tibet in the Departments of Anesthesiology was lower than that of non-commissioned trainees (Z=–4.543, P<0.001). There were statistically significant differences in 7 of the 25 operating data (P<0.05). The operation number of arterial puncture and ventilator management (Intensive Care Unit); patient treatment (Department of Emergency); arterial puncture, ventilator management and intraoperative monitoring (Department of Anesthesiology) of trainees from Tibet were lower than those of non-commissioned trainees (P<0.05). The operation number of lung and mediastinal examinations (Department of Radiology) of trainees from Tibet was higher than that of non-commissioned trainees (P<0.05).ConclusionsDuring the training of the two types of trainees, the rotation schedule was basically the same, but there were differences in the clinical practice operations. Trainees from Tibet have higher requirements for radiology training. Trainees from Tibet will return to Tibet with independent practice needs, so their requirements of medical imaging skills operation would be higher. Due to language and training time, the critically ill, emergency first aid, and surgical skills of trainees from Tibet are not as good as those of non-commissioned trainees, and they need to gradually strengthen and improve these skills in subsequent trainings.